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Muscle-Tendon-Innervation Unit: Degeneration and Aging - Pathophysiological and Regeneration Mechanisms
Aging is characterized by progressive deterioration of walking ability. This function loss has multiple causes including central and peripheral nerve dysfunction, loss of muscle mass and strength, as well as joints and bone alterations. Muscle-tendon unit and its innervation has a pivotal role in motor function performance that can be disrupted by overuse degeneration and aging. Research has shown that overuse degeneration and aging also share some pathophysiological mechanisms including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and modification of signalling and stress response pathways. This Research Topic is intended to bring together basic researchers and clinicians working in the area of neuroscience, aging, sarcopenia and orthopaedics in human and in animal models. The aim of this cross-fertilization is to accelerate our understanding of the mechanisms involved in aging and degeneration of the muscle-tendon unit and its innervation and to explore the therapeutic potential of pharmacological and physical therapy interventions.
Gully Erosion Studies from India and Surrounding Regions
This book offers the scientific basis for the ample evaluation of badland management in India and some surrounding regions. It examines the processes operating in the headwaters and main channels of ephemeral rivers in lateritic environments of India. In particular, the book covers a range of vital topics in the areas of gully erosion and water to soil erosion at lateritic uplands regions of India and other regions in Asia. It explores the probable gully erosion modeling through Remote Sensing & GIS Techniques. It is divided into three units. Unit I deals with the introduction of badland, types of badland and the process of badland formation. Unit II is devoted to a description of quantitative measurements. Unit III deals with the control and management processes related to various issues from different regions. As such this book serves as a reference book for research activities in this area. It is an efficient guide for aspiring researchers in applied geography, explaining advanced techniques to help students recognize both simple and complex concepts.
State and Corporate Management of Region’s Development in the Conditions of the Digital Economy
This edited book presents scientific and practical recommendations for the successful state and corporate management of regional development under the conditions of the digital economy. These conditions have produced a number of changes. On the one hand, new aspects of regional economies, which require management, are emerging, above all, digital technologies that have to be understood by the population, employees in the labor market, and regional companies. On the other hand, new opportunities for improving practices in the state and corporate management of regional development on the basis of digital technologies are also emerging: e-government systems, digital marketing, online trade, “smart” regions, etc. This book provides an overview of the leading digital technologies and demonstrates how they can be used to improve modern practices in the state and corporate management of regional development in the digital economy. The authors develop the conceptual foundations and put forward practical recommendations. In closing, the authors’ conclusions and recommendations are applied to the example of modern Russia, ensuring the practical relevance of the research.
Business 4.0 as a Subject of the Digital Economy
This book substantiates the transformation processes in the system of modern entrepreneurship in the conditions of formation of Industry 4.0. The authors develop a scientific concept of business 4.0, determine the specific features of business 4.0 and current problems and perspectives of its development in developed and developing markets, study the infrastructural provision of business 4.0 in view of its sectorial specifics, outline the perspectives and recommendations in the sphere of development of business 4.0, and offer the scientific and practical recommendations for state and corporate management.
Cultural Sustainable Tourism
This book is an assemblage of diverse yet homogenous research papers that bring together the issues and challenges of cultural heritage conservation and tourism sustainability. The richness of this book stems from its inclusion of diverse case studies from around the globe while scrutinizing the cases of both deterioration and sustainability of cultural heritage belonging to different eras. This book sheds light on the connections between culture as an essential dimension of local sustainability and cultural dimensions of sustainable tourism, further contributing to the complex discussion between culture and tourism. This book gives an overview of current research and subjects of discussion that focuses on cultural sustainable tourism through several sections, such as planning and management of sustainable tourism, sustainable cultural tourism development in a digital era, social and economic impacts of cultural tourism, and sustainable tourism development in urban areas
Mosque Architecture: A Transdisciplinary Debate
Against a backdrop of environmental and societal concerns, best captured by the UN’s Sustainable Development Goals (SDGs), this book brings together the leading voices on Mosque architecture to make a case for its role as a purveyor of culture, heritage, and sustainability in the modern world. The Mosque, as an institution, continues to serve as the epicenter of spiritual, moral, and cultural life in Muslim societies. Recognizing that the popular understanding of Muslim culture and archetypes is, at best, minimal among the broader public worldwide, this book has two objectives: i.e., (i) to explore Masjid architecture as a carrier of culture, heritage, and the sustainability of Muslim communities; and (ii) to offer a bias-free introduction to the intricacies of Muslim architecture, culture, and heritage today. The papers featured in this collection were presented at the 5th Memaryat International Conference (MIC), held at Effat University, Jeddah. The MIC’s objective is to build bridges between research communities engaged with diverse aspects of science, technology, and innovation, seen as the key levers for attaining the SDGs.
Advances in Geoethics and Groundwater Management : Theory and Practice for a Sustainable Development
This book gathers the peer-reviewed proceedings of the 1st congress on Geoethics & Groundwater Management (GEOETH&GWM'20), held in Porto, Portugal, in an online format on 18-22 May 2020. Hosted in School of Engineering (ISEP), Polytechnic of Porto based on Porto city (a UNESCO World Heritage Site), the international conference focused on what has now been dubbed “hydrogeoethics”, a novel transdisciplinary, scientific field integrating all dimensions of geoethics in groundwater science and practice. Given its scope, the book is of interest to all researchers and practitioners in the geosciences, hydrology, water resources, hydrogeology, natural resources management, environment, engineeri...
Advances in the Leading Paradigms of Urbanism and their Amalgamation
This book explores the recent advances in the leading paradigms of urbanism, namely compact cities, eco-cities, and data–driven smart cities, and the evolving approach to their amalgamation under the umbrella term of smart sustainable cities. It addresses these advances by investigating how and to what extent the strategies of compact cities and eco-cities and their merger have been enhanced and strengthened through new planning and development practices, and are being supported and leveraged by the applied solutions pertaining to data-driven smart cities. The ultimate goal is to advance sustainability and harness its synergistic effects on multiple scales. This entails developing and impl...
Cities’ Vocabularies: The Influences and Formations
This book discusses several topics regarding different vocabularies, such as sacred architecture, heritage buildings, open spaces, landmarks, and street escapes, all of which have a direct influence on the city form. The city form is also affected by the indirect impact of the citizens themselves, for example their culture, which in turn depends on the arts, as can be seen and embodied in morals, paintings, media, digital art, and sculpture. The book also examines the fundamental elements that are responsible for the identity of the city. Presenting case studies that demonstrate the how implementing the concept of the responsibility of architecture and arts affects the development of our cities, the book offers a new approach that is based on the available features of a city and explores how planners and decision-makers can use these features to address the myriad problems that our cities are facing.
