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The 49Th Scientific meeting of the Italian Statistical Society was held in June 2018 in Palermo, with more than 450 attendants. There were plenary sessions as well as specialized and solicited and contributed sessions. This volume collects a selection of twenty extended contributions covering a wide area of applied and theoretical issues, according to the modern trends in statistical sciences. Only to mention some topics, there are papers on modern textual analysis, sensorial analysis, social inequalities, themes on demography, modern modeling of functional data and high dimensional data, and many other topics. This volume is addressed to academics, PhD students, professionals and researchers in applied and theoretical statistical models for data analysis.
"This book proposes an articulated and multidisciplinary research path that introduces to the potential of adopting territorial statistics, namely those elaborated at the level of Local Labour Systems, for carrying out spatial analysis of apparent and latent interactions between socioeconomic phenomena and environmental dynamics at a sufficiently broad and efficient geographical unit of analysis. This allows to examine in a more exhaustive manner the complexity and non-linearity of several socio-economic and territorial processes and to address the multidimensional concept of sustainability from below. Studies included in this book contribute to an integrated, multidisciplinary reading that covers the three pillars of sustainability. Italy is a relevant case study in this sense and can be assumed as a paradigmatic country also for other advanced European nations that undertook territorial analysis at a very disaggregated spatial level (i.e., UK, Spain, Germany and France among others)"--
This book represents proceedings of the 19th American Peptide Symposium. It highlights many of the recent developments in peptide science, with a particular emphasis on how these advances are being applied to basic problems in biology and medicine. Specific topics covered include novel synthetic strategies, peptides in biological signaling, post-translational modifications of peptides and proteins, and peptide quaternary structure in material science and disease.
Folded peptides - and peptide motifs within proteins - are abundant in living organisms, where they are essential for the biological activities of the peptides and proteins. During the past decades, much research has been dedicated to understanding the rules that govern peptide folding. Simultaneously, a range of strategies have been established for the conformational stabilization of bioactive peptides, as well as for the de novo design of peptides with defined secondary structures. These methods are either based on the chemical modification of the peptide backbone, such as cyclization and stapled peptides, or on the use of a range of non-proteinogenic amino acids that, in a defined sequent...
This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.
Newly-discovered evidence underpins this comprehensive account of the creation and staging of the earliest surviving 'opera', Euridice.
This atlas aims to present sound approaches to maturity sampling for a wide range of Mediterranean species – including bony fish, cartilaginous fish, both oviparous and viviparous, crustaceans and cephalopods – based on an accurate determination of the different maturity stages. It includes macroscopic photos of gonads belonging to the main species and, for some, a validation-based histological analysis.