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Now in paperback, the second edition of the Oxford Textbook of Critical Care addresses all aspects of adult intensive care management. Taking a unique problem-orientated approach, this is a key resource for clinical issues in the intensive care unit.
Part of the World Clinics series, this book is the second volume of the pulmonary and critical care medicine manuals and focuses on chronic obstructive pulmonary disease (COPD). The book begins with the epidemiology and pathophysiology of COPD, followed by chapters covering topics in the diagnosis and management of the disease, including acute exacerbations, imaging, biomarkers, oxygen therapy and vascular dysfunction. The final sections present a complete review of pulmonary disease and rehabilitation. This new volume includes numerous images, illustrations and tables to enhance the text. The previous volume in this series, Pneumonias, published in 2012. Key points Second volume covering chronic obstructive pulmonary disease (COPD) Part of the World Clinics: Pulmonary and Critical Care Medicine series Includes nearly 100 images, illustrations and tables Volume One published in 2012
Chlamydia pneumoniae is a bacteria that is most commonly known for causing colds and pneumonia. However, researchers have recently found a link between C. pneumoniae and atherosclerosis, a clogging of the arteries that causes heart attack and stroke. In addition, ongoing research is showing that certain strains may play a role in asthma, multiple sclerosis, Alzheimer's disease, and arthritis. This volume, part of the Infectious Agents and Pathogenesis series, is a complete portrait of C. pneumoniae and what is currently known about it.
The Fourteenth Washington International Spring Symposium, held in Washington, D.C., in June 1994, brought together over 400 leading scientists from 21 countries to review and update research on cardiovascular disease. This group satisfied the symposium goals of formulating a more comprehensive and integrated picture of the events contributing to atherosclerosis and of exploring modified gene expression as an to understanding the causes of atherosclerosis and providing clues to the approach prevention and treatment. This volume contains most of the papers presented at the eight plenary sessions together with selected contributions from the special sessions. The multidisciplinary nature of the...
Over the last decade, the volume of research into the pathophysiology and genetics of pulmonary diseases has increased greatly. This has led to the development of new treatments and therapies for many diseases, including lung cancer, asthma and cystic fibrosis. This issue of the ERS Monograph comprehensively demonstrates the developments in respiratory medicine in recent years. It outlines the importance of epidemiology in respiratory medicine, and will prove a methodological tool that will help disease management. It should also be used as an advocacy tool for the sake of public health.
As suggested by the title of this Special Issue, liquid chromatography-mass spectrometry plays a pivotal role in the field of proteomics. Indeed, the research and review articles published in the Issue clearly evidence how the data produced by this sophisticated methodology may promote impressive advancements in this area. From among the topics discussed in the Issue, a few point to the development of new procedures for the optimization of the experimental conditions that should be applied for the identification of proteins present in complex mixtures. Other applications described in these articles show the huge potential of these strategies in the protein profiling of organs and range from to the study of post-translational tissue modifications to the investigation of the molecular mechanisms behind human disorders and the identification of potential biomarkers of these diseases.
Community-acquired pneumonia remains the leading cause of hospitalisation for infectious disease in Europe, and a major cause of morbidity and mortality. This issue of the European Respiratory Monograph brings together leading experts in pulmonology, infectious diseases and critical care from around the world to present the most recent advances in the management of community-acquired pneumonia. It provides a comprehensive overview of the disease, including chapters on microbiology, pathophysiology, antibiotic therapy and prevention, along with hot topics such as viral pneumonias and pneumonia associated with inhaled corticosteroids.
The European Respiratory Society (ERS) Handbook of Respiratory Medicine, now in its third edition, is a concise, compact and easy-to-read guide to each of the key areas in respiratory medicine. Its 20 sections, written by clinicians and researchers at the forefront of the field, explain the structure and function of the respiratory system, its disorders and how to treat them. The Handbook is a must-have for anyone who intends to remain up to date in the field, and to have within arm's reach a reference that covers everything from the basics to the latest developments in respiratory medicine.
Bronchiectasis is a hot topic in respiratory medicine, attracting an increasing amount of interest from clinicians, scientists, physiotherapists and the pharmaceutical industry. However, there is a lack of knowledge about the disease in terms of the research performed, clinical management, classification and patient treatment. The disease is also very complex because it can be caused by multiple underlying disorders, meaning its clinical presentation is highly diverse. This Monograph will tackle these issues by providing a series of chapters from recognised world experts covering: clinical management, service delivery, pathophysiology, microbiology and underlying disorders. The book also addresses the challenges faced in clinical trials and the need for drug development, and presents a number of clinical cases designed to aid learning. The Bronchiectasis Monograph substantially integrates the 2017 ERS guidelines on management of these patients. It is an essential reference for anyone caring for bronchiectasis patients or engaged in bronchiectasis research.
Current Topics in Cellular Regulation, Volume 19 analyzes the advances in the general area of cellular regulation. This book discusses the evidence indicating that synthesis of the histidine enzymes is regulated and drugs affecting ribonucleotide reductase. The analogy principle in comparative biochemistry of allosteric regulation of metabolism, steady-state model of glucose metabolism in adipose tissue, and sensitivity of enzyme activity to changing ion concentrations are also elaborated. This publication likewise covers the cAMP-dependent protein kinases of nervous tissue and amino acid sequences of IGF I and II. This volume is a good reference for biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.