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Biomarkers of Brain Damage – A Complex Challenge with Great Potential
Olli Tenovuo is consultant and member of SAB for NeuroTrauma Sciences LLC (Georgia, USA) and ABCDx SA (Geneva, Switzerland). Jean-Charles Sanchez has a research grant to disclose from ABCDx SA, (Geneva, Switzerland). Damir Janigro is the CEO of FloTBI Inc. (Cleveland, USA), a company interested in biomarkers of neurological diseases.
Neurodegenerative Diseases
Neurodegenerative Diseases - Processes, Prevention, Protection and Monitoring focuses on biological mechanisms, prevention, neuroprotection and even monitoring of disease progression. This book emphasizes the general biological processes of neurodegeneration in different neurodegenerative diseases. Although the primary etiology for different neurodegenerative diseases is different, there is a high level of similarity in the disease processes. The first three sections introduce how toxic proteins, intracellular calcium and oxidative stress affect different biological signaling pathways or molecular machineries to inform neurons to undergo degeneration. A section discusses how neighboring glia...
Update on Amyotrophic Lateral Sclerosis
This book contains selected peer-reviewed chapters which cover updated information on ALS written by international researchers. Update on Amyotrophic Lateral Sclerosis is comprised of 13 chapters from some of the world's top central nervous system researchers and neurologists to provide a timely review of the most recent developments in ALS, covering historic aspects, experimental animal models, genetics, pathogenesis, clinical aspects and imagenology among others. Contributors from Belgium, France, Japan, India, Italy, Mexico, Russia, South Africa, and Switzerland have collaborated enthusiastically and efficiently, dedicating their time to create this reader-friendly yet comprehensive work which includes many explanatory figures, tables and photos to enhance legibility and make the book clinically useful. We are looking forward with confidence and pride in the remarkable role that this book will play for a new vision and mission.
Parkinson's Disease and Beyond
Parkinson's Disease and Beyond - A Neurocognitive Approach aims to bring together in a single publication the knowledge of diagnosis and characterization of the clinical and neuropsychological profile in Parkinson's disease. The strong impulse to research this topic has produced in recent years a large literature that documents the high level of complexity of the issue. Due to this complexity, a reasoned multidimensional analysis able to integrate expertise of different disciplines (neurology, neuropsychology, neuroradiology, and neuroscience) is necessary. This book offers an excellent synopsis of perspectives, methods, empirical evidences, and international references. It represents an extraordinary opportunity to target challenging unmet needs and to outline new horizons in Parkinson's disease research.
Environmental Enrichment: Enhancing Neural Plasticity, Resilience, and Repair
The collection of articles in this eBook focuses on important issues related to environmental enrichment including standardization, neurobehavioral and physiological effects across the age axis, neuroprotection and plasticity, and implications for translation. Evaluation of key parameters and issues related to standardization is important for promoting species-typical behavior and broader adaptation and translation to clinical settings. Furthermore, understanding seminal mechanisms contributing to the effects of environmental enrichment in both biological sexes is also important for the application of this housing condition to preclinical models of neurological and psychiatric disorders. Taken together, this body of work points to the relevance of enriched housing environments in laboratory practice and the potential for translation to clinical populations.
Psoriasis
In 2014, psoriasis was recognized as a serious noncommunicable disease in the World Health Assembly Resolution WHA67.9, with a great negative impact on patients' quality of life. Psoriasis is a worldwide chronic disease, affecting all ages and all races, and a serious global health problem. Psoriasis is a complex disease with still unknown etiology and no specific curative treatment. The chapters provide comprehensive and new description of some issues related to psoriasis research and for understanding of clinical correlations, genetic aspects, experimental research, and potential therapeutic interventions. The book could be a source of information for clinicians and researchers from different fields in raising awareness of the disease.
