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ImmunoPhysics and ImmunoEngineering
ImmunoPhysics (ImmPhys) and ImmunoEngineering (ImmPhysEng), are two cross-disciplinary fields. ImmPhysEng aims to unravel quantitatively the immune-system function and regulation in health and disease. Whereas ImmPhys study and assess the physical basis of the immune response, ImmEng pursues its control and prediction. Ultimately, the overarching goal of these disciplines is to facilitate the development of therapeutic interventions to more precisely modulate and control the compromised immune response during diseases. Lately, these disciplines are becoming more popular and as such, the number of publications applying physical or engineering tools to understand the immune response is increasing. Nevertheless, there is still no scientific forum compiling the ImmPhysEng research breakthroughs. Possibly the biggest burden is to stimulate a fluent communication and syntony between a physicist or engineer and an immunologist.
Tetraspanins
Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in which the role of tetraspanins have been established and also covers the molecular evolution of the tetraspanin superfamily and structural aspects of the organisation of tetraspanin microdomains.
Inhibitory Receptors and Pathways of Lymphocytes
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Cell Migration in Inflammation and Immunity
Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases. About 50 distinct chemokines produced by a variety cell types and tissues either c- stitutively or in response to inflammatory stimuli are involved in a plethora of biological processes. These small secreted proteins exert their exquisitely variegated functions upon binding to a family of seven-transmembrane spanning G-protein coupled receptors (GPCRs) composed of almost 20 distinct entities. The biological activities of chemokines range from the control of leukocyte trafficking in basal and inflammatory conditions to the regulation of hema- poiesis, angio...
Encyclopedia of Renaissance Philosophy
Gives accurate and reliable summaries of the current state of research. It includes entries on philosophers, problems, terms, historical periods, subjects and the cultural context of Renaissance Philosophy. Furthermore, it covers Latin, Arabic, Jewish, Byzantine and vernacular philosophy, and includes entries on the cross-fertilization of these philosophical traditions. A unique feature of this encyclopedia is that it does not aim to define what Renaissance philosophy is, rather simply to cover the philosophy of the period between 1300 and 1650.
The Politics of Editing
Editing is by nature an interpretive practice, framed by the editor's circumstances mediating between the author's or text's 'authority, ' the contingencies of numerous institutions of literary and cultural production, and a variety of expectations that arise from the specific social and historical conditions of the readers.
Adhesion Protein Protocols
Adhesion molecules are of fundamental importance in the regulation of immunity, inflammation, tissue remodeling, and embryonic development. They comprise different families of homologous proteins, such as selectins, integrins, cadherins, and immunoglobins. In addition, beyond these groups, other str- tures with adhesive properties, such as proteoglycans, occludin, and CD44, have been characterized recently. An understanding of the type and characteristics of adhesive molecules expressed by the different cell types and the possibility of manipulating their activity promises considerable clinical potential. Antibodies, small peptidic and nonpeptidic molecules, have recently been used to inhibi...
