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Tetraspanins
Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in which the role of tetraspanins have been established and also covers the molecular evolution of the tetraspanin superfamily and structural aspects of the organisation of tetraspanin microdomains.
Iberian Books / Libros ibéricos (IB)
This is the first comprehensive listing of all books published in Spain, Portugal, Mexico and Peru or in Spanish or Portuguese before 1601. Iberian Books offers an analytical short title-catalogue of over 19,000 bibliographically distinct items, with reference to around 100,000 surviving copies in over 1,200 libraries worldwide. By drawing together information from many previously disparate published and online resources, it seeks to provide a single, powerful research resource. Fully-indexed, Iberian Books is an indispensible work of reference for all students and specialists interested in the literature, history and culture of the Iberian Peninsula in the early modern age, as well as historians of the European book world. For the period 1601-1650, see Iberian Books Volumes II & III.
The Politics of Editing
Editing is by nature an interpretive practice, framed by the editor's circumstances mediating between the author's or text's 'authority, ' the contingencies of numerous institutions of literary and cultural production, and a variety of expectations that arise from the specific social and historical conditions of the readers.
Cell Migration in Inflammation and Immunity
Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases. About 50 distinct chemokines produced by a variety cell types and tissues either c- stitutively or in response to inflammatory stimuli are involved in a plethora of biological processes. These small secreted proteins exert their exquisitely variegated functions upon binding to a family of seven-transmembrane spanning G-protein coupled receptors (GPCRs) composed of almost 20 distinct entities. The biological activities of chemokines range from the control of leukocyte trafficking in basal and inflammatory conditions to the regulation of hema- poiesis, angio...
Structure, Function, and Regulation of Molecules Involved in Leukocyte Adhesion
Leukocyte adhesion molecules have been the subject of intense basic and preclinical research. Results from clinical trials obtained sofar with antibodies directed towards these surface proteins offer promise for the prevention of graft rejection and effective treatment of acute and chronic inflammatory disease. This volume presents a comprehensive review of contemporary research on the structure, function and regulation of leukocyte adhesion molecules and their ligands, from the molecular to the clinical level. The blend of basic science and clinical applications presented in Structure, Function and Regulation of Molecules Involved in Leukocyte Adhesion provides clear evidence of the biological importance of cell-cell interactions and the many potential clinical dividends afforded by understanding the molecular basis of cell adhesion. It will appeal to a broad range of readers in immunology and cell biology.
Cell Adhesion Molecules
The Fourth Annual Pezcoller Symposium entitled Adhesion Molecules: Cellular Recognition Mechanisms was held in Rovereto, Italy, June 24-26, 1992 and was focussed on the detailed mechanisms whereby cells utilize certain integral membrane proteins to perceive their surrounding environment and interact with it. With timely presentations and stimulating discussions this Symposium addressed the genetics and biochemistry of adhesion molecules, the regulation of their functions and their role in cancer and the immune system. Emphasis was given to adhesion proteins in the integrin family because of the widespread distribution of this group of molecules and its important role in essentially all eukar...
Cell Adhesion and Human Disease
Experts in their respective fields present papers concerned with the range of human diseases caused by defective or abnormal functioning of cell adhesion molecules. Discusses new therapeutic approaches to these maladies.
