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Tetraspanins
Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in which the role of tetraspanins have been established and also covers the molecular evolution of the tetraspanin superfamily and structural aspects of the organisation of tetraspanin microdomains.
Making Room
Mentally ill people turned out of institutions, crack-cocaine use on the rise, more poverty, public housing a shambles: as attempts to explain homelessness multiply so do the homeless--and we still don't know why. The first full-scale economic analysis of homelessness, Making Room provides answers quite unlike those offered so far by sociologists and pundits. It is a story about markets, not about the bad habits or pathology of individuals. One perplexing fact is that, though homelessness in the past occurred during economic depressions, the current wave started in the 1980s, a time of relative prosperity. As Brendan O'Flaherty points out, this trend has been accompanied by others just as un...
The Rubinstein Attack!
The book discusses in detail the chess opening known as the Rubinstein Attack, and presents analysis and typical games in all the main branches of the opening. This opening system for White can provide the basis for a solid opening strategy that nevertheless provides great opportunities to launch effective attacks against the enemy king. It has been used by many top chessplayers and has been seen in many important tournament encounters. The author presents key middlegame concepts in fully annotated games, so that the reader learns how to carry out the various forms of attack. See other books by Dr. Schiller: Of Kings and Pawns: Chess Strategy in the Endgame, US $17.95
Sellars and Contemporary Philosophy
Wilfrid Sellars made profound and lasting contributions to nearly every area of philosophy. The aim of this collection is to highlight the continuing importance of Sellars’ work to contemporary debates. The contributors include several luminaries in Sellars scholarship, as well as members of the new generation whose work demonstrates the lasting power of Sellars’ ideas. Papers by O’Shea and Koons develop Sellars’ underexplored views concerning ethics, practical reasoning, and free will, with an emphasis on his longstanding engagement with Kant. Sachs, Hicks and Pereplyotchik relate Sellars’ views of mental phenomena to current topics in cognitive science and philosophy of mind. Fink, deVries, Price, Macbeth, Christias, and Brandom grapple with traditional Sellarsian themes, including meaning, truth, existence, and objectivity. Brandhoff provides an original account of the evolution of Sellars’ philosophy of language and his project of "pure pragmatics". The volume concludes with an author-meets-critics section centered around Robert Brandom’s recent book, From Empiricism to Expressivism: Brandom Reads Sellars, with original commentaries and replies.
Guidebook to the Extracellular Matrix, Anchor, and Adhesion Proteins
Intended for postgraduate and professional researchers in biochemistry, biomedical sciences and cell biology, this text offers a guide to the extracellular matrix and adhesion proteins.
Functional Relevance of Tetraspanins in the Immune System
Tetraspanins are small (20-50 kDa) integral membrane proteins with four transmembrane domains that have an intrinsic propensity to associate with other membrane proteins and lipids giving rise to the formation of specific tetraspanin-enriched microdomains (TEMs), also referred to as “The tetraspanin web”. In mammals, the tetraspanin family comprises of 33 different members, with the majority of the members being abundantly expressed in almost all cell types, including leukocytes which are responsible for innate and adaptive immunity as well as in other cells that play pivotal roles in immune responses, such as endothelial or stromal cells. Therefore, through the wide range of specific molecular interactions in which they are engaged, tetraspanins influence many processes of up-most relevance in the development, physiology and pathology of the immune system, including the control of immune cell morphology, signaling, adhesion, migration, invasion, fusion, infections and cancer.
Scribal Memory and Word Selection
What were ancient scribes doing when they copied a manuscript of a literary work? This question is especially problematic when we realize that ancient scribes preserved different versions of the same literary texts. In Scribal Memory and Word Selection: Text Criticism of the Hebrew Bible, Raymond F. Person Jr. draws from studies of how words are selected in everyday conversation to illustrate that the same word-selection mechanisms were at work in scribal memory. Using examples from manuscripts of the Hebrew Bible, Person provides new ways of understanding the cognitive-linguistic mechanisms at work during the composition/transmission of texts. Person reveals that, while our modern perspective may consider textual variants to be different literary texts, from the perspective of the ancient scribes and their audiences, these variants could still be understood as the same literary text.
Interplay Between Immunity and Fibrosis
Topic Editor Prof. Oliver Distler received financial support from Actelion, Bayer, Boehringer Ingelheim, Mitsubishi Tanabe Pharma companies. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Change Is Possible
Based on dozens of interviews and extensive historical research, and spiced with interesting photographs, this entertaining book relates stories about mathematicians who have defied stereotypes. There are five chapters about women that provide insight into the nineteenth and the mid-twentieth century, the early 1970s, the early 1990s, and 2004. Activists in many fields will take heart at the progress made during that time. The author documents the rudimentary struggles to become professionals, being married without entirely giving up a career, organizing to eliminate flagrant discrimination, improving the daily treatment of women in the professional community, and the widespread efforts towa...
LIFE
LIFE Magazine is the treasured photographic magazine that chronicled the 20th Century. It now lives on at LIFE.com, the largest, most amazing collection of professional photography on the internet. Users can browse, search and view photos of today’s people and events. They have free access to share, print and post images for personal use.
