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Biomarkers for Alzheimer’s Disease Drug Development
This volume aims to build a new generation of experts with a broader understanding of key topics in the Alzheimer’s disease field. Chapters guide readers through innovative approaches to the discovery of novel biomarkers in cerebrospinal fluid, innovation in blood-based biomarkers, a comprehensive overview of magnetic resonance imaging and molecular imaging approaches and their value for developing drugs for Alzheimer’s disease, cutting-edge developments in neuropathology and their relevance for Alzheimer’s disease trials, novel genomic strategies for biomarker development, and related topics including neuropsychological testing and advanced analytical methods.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Biomarkers for Alzheimer's Disease Drug Development aims to ensure successful results in the further study of this vital field.
ACSM's Guidelines for Exercise Testing and Prescription
The flagship title of the certification suite from the American College of Sports Medicine, ACSM's Guidelines for Exercise Testing and Prescription is a handbook that delivers scientifically based standards on exercise testing and prescription to the certification candidate, the professional, and the student. The 9th edition focuses on evidence-based recommendations that reflect the latest research and clinical information. This manual is an essential resource for any health/fitness and clinical exercise professional, physician, nurse, physician assistant, physical and occupational therapist, dietician, and health care administrator. This manual give succinct summaries of recommended procedures for exercise testing and exercise prescription in healthy and diseased patients.
Cerebral Small Vessel Disease
Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
Exercise Physiology
Abstract: This third edition of the book integrates basic concepts and relevant scientific information to provide the foundation for understanding nutrition, energy transfer, and exercise and training. Designed for both the beginning and advanced student, the subjects covered include energy for physical activity, systems of energy delivery and utilization, enhancement of energy capacity, work performance and environmental stress, body composition, energy balance, and weight control, and the metric system and SI units.
Handbook of Computer Aided Geometric Design
This book provides a comprehensive coverage of the fields Geometric Modeling, Computer-Aided Design, and Scientific Visualization, or Computer-Aided Geometric Design. Leading international experts have contributed, thus creating a one-of-a-kind collection of authoritative articles. There are chapters outlining basic theory in tutorial style, as well as application-oriented articles. Aspects which are covered include: Historical outline Curve and surface methods Scientific Visualization Implicit methods Reverse engineering. This book is meant to be a reference text for researchers in the field as well as an introduction to graduate students wishing to get some exposure to this subject.
International Arbitration in Sweden
International Arbitration in Sweden', now in its second edition, is a compendious book penned by sixteen eminent practitioners that furnishes a practical guide to international arbitration in Sweden, whether ad hoc or institutional. Sweden is one of a handful of countries where the international arbitral process has reached a stage where the jurisprudence is replete with instances involving no local parties at all. In this context of credible neutrality, the Arbitration Institute of the Stockholm Chamber of Commerce (SCC) has emerged as a leading global arbitral institution. Whether the matter at issue is a business transaction dispute or a politicized conflict involving obdurate parties, the richness of its body of decided cases manifests the SCC?s authority and reliability throughout the converging world of international arbitration.
Essentials of Otolaryngology
Thoroughly revised and updated for its Fifth Edition, this handy pocket manual presents step-by-step guidelines on patient workup, differential diagnosis, and therapy for more than 40 symptoms occurring in the head and neck region. The authors outline current treatment recommendations and offer primary care physicians advice on indications for referral. Also included are chapters on anatomy and physiology, history taking, physical examination, occupational medicine, radiation therapy, chemotherapy, and pediatric, adolescent, and geriatric otolaryngology, as well as an introduction to outcome analysis and office-based clinical research. This edition features several new chapters, including pain management and use of lasers in otolaryngology.
