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Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health. It addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology. In addition to covering the traditional subject matter of toxicology, special emphasis has been placed on recent areas of interest, such as risk assessment, apoptosis, and methodical developments.Key Features* Comprehensive text, covering all aspects of the field of toxicology* Analyzes the importance of toxicokinetics and metabolism as well as cellular targets for the mechanisms of toxic effects* Identifies the various classes of chemical compounds responsible for the toxic effects* Describes the approaches and methods used by various disciplines which investigate toxic effects and their prevention* Adapted from a very successful German text, this edition is completely revised and expanded * The text is well illustrated with diagrams, charts, and tables
Forensic Pharmacology explores the many links between drugs and forensic science, from drug-induced violence and crime to determining whether a person taking a certain medication is capable of standing trial for a crime, to the forgery of prescriptions. The reader is introduced to the daily work of the scientists, and the principles of pharmacology and toxicology, as well as the various classes and technical analysis of drugs of abuse.
Too much emotion and insufficient fact. This paradox has long characterized the controversy surrounding animal research. Of Mice, Models, and Men is the first exhaustive treatment of all areas—empirical and conceptual—relevant to the use of animals in research. It is also the first study to combine regard for the welfare of laboratory animals with a knowledgeable acceptance of the continuing need for research involving animals. The book has another rare quality. It is virtually devoid of any of the emotional and exaggerated attacks that have characterized many of the other publications in this area. Instead, it presents, in a manner accessible to both sides, all the relevant historical, social, and scientific information required to form an opinion on the subject. The book thus achieves a most difficult goal—that of bridging the gap between researchers using animals and animal welfare advocates, while pointing out the need for a more active program to promote laboratory animal welfare.
Why Efforts to Expand the Meaning of "Teratogen" Are Unacceptable Disagreement about nomenclature in teratology is not new. Dissent even about the very fabric of the discipline-what congenital malformations consist of-has often been voiced. Time, instead of resolving such diffi culties, has sometimes worsened them. For example, in the past it was agreed that congenital malforma tions are abnormalities of structure present at birth, but differences of opinion concerning where the line between normal and abnormal was to be drawn prevailed. It was obvious that, in order to discover the causes of congenital malformations and cast strategies for their prevention, it would be necessary to have knowledge of the baseline of their frequency, and that this required uniformity of definition of terms. Since malfor mations of primary social concern are those having grave outcomes (and are, paradoxically, also the commonest ones), it is logical that such condi tions were the first consideration of investigators and were the defects whose frequency was considered to comprise the required baseline.
Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology expe
This story is based on a true love story that spanned almost two decades. The names and places have been changed to protect the privacy of the individuals involved in this affair. The chronological sequence of events has been maintained for continuity. All the stories and experiences are based on facts. This book is about a love story that was kept secret for 18 years and perhaps shouldve remained a secret. The first book related to this love story was a book of poems entitled Somewhere, Sometime, Somehow: Love Poems and Short Stories published in 2008 by this author and Xlibris. For the perceptive reader of this book one can trace the ups and downs of our love relationship. These 18 years w...
This important publication addresses intercellular communication in health and disease. It includes recent advances in morphology and chemical organization of gap junctions. It discusses the possible role of intercellular channels in excitable and non-excitable tissues. The book presents modulation of junctional permeability, as well as the possible role of cell communication in embryonic development and growth. The text concludes with a synthetic view of the role of gap junctions and potential implications to cardiology, oncology, and other areas of pathology. This volume is important to professionals in pharmacology, physiology, biochemistry, biomedical science, pathobiology, pathology, molecular genetics, toxicology and human development.