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The Somatotrophic Axis in Brain Function
  • Language: en
  • Pages: 365

The Somatotrophic Axis in Brain Function

  • Type: Book
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  • Published: 2005-12-12
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  • Publisher: Elsevier

The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being reduced in depression.This volume will include chapters (1) on basic knowledge on GH/IGF-1, (2) on loca...

Blood-Spinal Cord and Brain Barriers in Health and Disease
  • Language: en
  • Pages: 623

Blood-Spinal Cord and Brain Barriers in Health and Disease

  • Type: Book
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  • Published: 2003-12-21
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  • Publisher: Elsevier

Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma. Key Features * Presents the recent progress made in the research on the blood-brain and spinal cord barrier * Contains numerous illustrations of light and electron micrographs * Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro

Handbook of Biologically Active Peptides
  • Language: en
  • Pages: 1682

Handbook of Biologically Active Peptides

  • Type: Book
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  • Published: 2011-04-28
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  • Publisher: Elsevier

Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for indiv...

Brain Damage
  • Language: en
  • Pages: 298

Brain Damage

"Brain Damage - Bridging Between Basic Research and Clinics" represents a collection of papers in an attempt to provide an up-to-date approach to the fascinating topic of brain damage in different pathological situations, combining the authors' personal experiences with current knowledge in this field. In general, the necessary link between basic and clinical neurosciences is highlighted, as it is through this interaction that the theoretical understanding of the pathophysiological mechanisms can be successfully translated into better ways to diagnose, treat and prevent the catastrophic events that occur when the brain suffers from external or internal noxious events. The book spans different aspects of brain injury, starting from damage occurring in the fetal and child brain, followed by different neurodegenerative processes. Attention is also focused on the negative effects of drug addictions and sleep deprivation on the brain, as well as on the early assessment of brain injury for preventive strategies employing sensitive biomarkers.

New Concepts of Psychostimulants Induced Neurotoxicity
  • Language: en
  • Pages: 501

New Concepts of Psychostimulants Induced Neurotoxicity

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. With recent advancements in new knowledge, it has become evident that psychostimulants and related drugs of abuse are influencing our central nervous system (CNS) remarkably and could alter their function for a longtime. This volume is the first to focus on substance abuse induced brain pathology in the widest sense as it covers alterations in neuronal, glial and endothelial cell functions under the influence of acute or chronic usage of substance abuse.

New Perspectives of Central Nervous System Injury and Neuroprotection
  • Language: en
  • Pages: 420

New Perspectives of Central Nervous System Injury and Neuroprotection

Annotation Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Reviews written by experts in such a way thatprovides basic knowledge for beginners and advanced information for researchers and experts. New aspects of Neurodegenerative diseasessuch as;Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis are presented with thelatest therapeutic measures. Exacerbation of brain pathology in hypertension or diabetes is discussed for the first time.

Scroll Zombies: How Social Media Addiction Controls our Lives
  • Language: en
  • Pages: 151

Scroll Zombies: How Social Media Addiction Controls our Lives

Almost everyone is doing it. Aimlessly scrolling through their social media feeds. From presidents to the postmen, most people you know and probably even yourself. Mindlessly, your fingers move across the screen, and content, from selfies to memes, flickers by at a blistering pace. Why is it that the screen sometimes seems more important than looking up and being present in real life? And what does it mean that more and more people are turning into so-called "Scroll Zombies"? Sven Rollenhagen thoughtfully discusses social media use and how it affects us both psychologically and physically. How the rise of social media has created an onslaught of mental health problems in young people. And ho...

Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome
  • Language: en
  • Pages: 572

Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome

This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments. - This volume of brings together research on tourettes synrdrome. It reviews current knowledge and understanding on the neurochemistry and neuropharmacology of tourettes syndrome

Axon Growth and Regeneration: Part 2
  • Language: en
  • Pages: 255

Axon Growth and Regeneration: Part 2

Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research. Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered. All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist - Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Proteases in the Brain
  • Language: en
  • Pages: 393

Proteases in the Brain

In all organs of the body, proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer’s, Parkinson’s and prion diseases, ischemia and traumatic brain injury, inflammatory and infectious diseases, and tumor progression. Proteases in the Brain brings together a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes. Proteases in the Brain reviews the role and regulation of proteases in, Alzheimer’s disease, brain i...