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Clinical Pancreatology
  • Language: en
  • Pages: 562

Clinical Pancreatology

Most patients suffering from pancreatic diseases are managed bygeneral internists, gastroenterologists and/or surgeons innon-specialized centers. Basic and clinical research inpancreatology is continuously leading to changes in the managementof pancreatic diseases, but these advances are applied to theclinical practice almost exclusively in specialized centers byspecialized groups. The books and journals currently available are directed atpancreatologists and the information does not reach most generalclinicians and surgeons who treat patients suffering frompancreatic diseases. The aim of this book is to provide practisinggastroenterologists and surgeons with clear information regardingthe diagnosis and treatment of pancreatic diseases.

Nanotechnology in Cancer Treatment
  • Language: en
  • Pages: 224

Nanotechnology in Cancer Treatment

  • Type: Book
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  • Published: 2020-12-16
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  • Publisher: MDPI

The collection is diverse in the topics covered as well as the contributors, who come from across the globe. The overall topic is inherently a complex one since it integrates the exceptional complexity of cancer biology and treatment with the large and rapidly growing number of potential nanostructures and modifications that could be applied to treatment. In both cancer and nanotechnology, a very small change of a relevant variable can generate exceptional variability in biological outcome, creating inherent challenges to clinical adoption. As with many high-potential fields in medicine, the recognition of exceptional potential for nanotechnology in cancer therapy, with associated expectatio...

Target Volume Definition in Radiation Oncology
  • Language: en
  • Pages: 359

Target Volume Definition in Radiation Oncology

  • Type: Book
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  • Published: 2015-04-15
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  • Publisher: Springer

The main objective of this book is to provide radiation oncologists with a clear, up-to-date guide to tumor delineation and contouring of organs at risk. With this in mind, a detailed overview of recent advances in imaging for radiation treatment planning is presented. Novel concepts for target volume delineation are explained, taking into account the innovations in imaging technology. Special attention is paid to the role of the newer imaging modalities, such as positron emission tomography and diffusion and perfusion magnetic resonance imaging. All of the most important tumor entities treated with radiation therapy are covered in the book. Each chapter is devoted to a particular tumor type and has been written by a recognized expert in that topic.

Glioblastoma: State of the Art and Future Perspectives
  • Language: en
  • Pages: 784

Glioblastoma: State of the Art and Future Perspectives

  • Type: Book
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  • Published: 2020-12-10
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  • Publisher: MDPI

Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research.

Informatics in Radiation Oncology
  • Language: en
  • Pages: 318

Informatics in Radiation Oncology

  • Type: Book
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  • Published: 2013-09-05
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  • Publisher: CRC Press

Reflecting the increased importance of the collaborations between radiation oncology and informatics professionals, Informatics in Radiation Oncology discusses the benefits of applying informatics principles to the processes within radiotherapy. It explores how treatment and imaging information is represented, stored, and retrieved as well as how t

Modification of Radiation Response
  • Language: en
  • Pages: 308

Modification of Radiation Response

This book describes and summarizes the radiation responses of both normal and neoplastic tissues with a focus on rational strategies for the modification of these responses. Emerging data from molecular oncology and radiobiology are reviewed in depth. The book covers not only general principles of radiation-induced reactions but also a large number of preclinical and clinical data that will guide the reader through this complex and dynamic field and will provide valuable information for the development of further research projects.

The History and Mystery of Breast Cancer
  • Language: en
  • Pages: 233

The History and Mystery of Breast Cancer

Breast cancer and its treatment is a terribly complex problem that involves all the intricacies of the human body, the anatomical and microscopic anatomy of the breast, the endocrine system, and bone metabolism, as well as the nature of malignant transformation. Even experts still have uncertainties. However, there is now an ethical and legal obligation for specialists to share their uncertainties with their patients when we are looking for informed consent before invasive procedures. Obsessive ruminations about the threat of breast cancer mean that few in the lay public know that breast cancer has slipped out of the top seven causes of death for women. Treatments for breast cancer might inc...

Short Course Breast Radiotherapy
  • Language: en
  • Pages: 489

Short Course Breast Radiotherapy

  • Type: Book
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  • Published: 2015-12-31
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  • Publisher: Springer

This comprehensive handbook on the implementation of short course radiotherapy for the treatment of breast cancer is intended as an up-to-date resource for the clinician. The book opens with a series of chapters on underlying principles and diverse relevant topics, including pathologic anatomy of early-stage breast cancer, radiobiology of accelerated breast irradiation, quality assurance and radiation safety, surgical considerations in partial breast irradiation, and impact of oncoplastic surgery on adjuvant radiotherapy. Individual sections are then devoted to hypofractionated whole breast radiotherapy, accelerated partial breast irradiation, and intraoperative radiotherapy. Each section includes details of patient selection, physics, techniques, data, and toxicity. The reader is provided with clear guidance on the appropriate use of accelerated forms of adjuvant radiotherapy for treatment of early-stage breast cancer and on various emerging treatment approaches.

Cell Signaling Mediating Critical Radiation Responses
  • Language: en
  • Pages: 181

Cell Signaling Mediating Critical Radiation Responses

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Intraoperative Radiotherapy (IORT) – A New Frontier for Personalized Medicine as Adjuvant Treatment and Treatment of Locally Recurrent Advanced Malignancy
  • Language: en
  • Pages: 76

Intraoperative Radiotherapy (IORT) – A New Frontier for Personalized Medicine as Adjuvant Treatment and Treatment of Locally Recurrent Advanced Malignancy

Intraoperative radiotherapy (IORT) is a treatment delivery technique with reports starting in the early 20th century. There are numerous advantages of IORT in oncology including delivery of a tumoricidal radiation dose in a single treatment, direct visualization of the treatment area of interest, decreasing dose to surrounding tissues, among others. In this series we focus on the clinical application, radiobiology and physics of IORT with an emphasis on the Intrabeam system. As medicine and health care continue to evolve the new frontier of personalized medicine must continue to rigorously evaluate and implement technologies that limit costs and provide meaningful therapeutic benefit.