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Discover the length and breadth of Germany with the most incisive and entertaining guidebook on the market. Whether you plan to check out Berlin's art galleries, cruise down the Rhine Valley or go wine-tasting along the Mosel Weinstrasse, The Rough Guide to Germany will show you the ideal places to sleep, eat, drink, shop and visit along the way. - Independent, trusted reviews written with Rough Guides' trademark blend of humour, honesty and insight, to help you get the most out of your visit, with options to suit every budget. - Full-colour maps throughout- navigate Rügen's meandering coastline or Munich's Altstadt without needing to get online. - Stunning images - a rich collection of ins...
This collection of essays covers relations between town and country, regional economic systems, and historical regional studies in late medieval and early modern Germany, in particular how these bear upon social and religious change in the age of the Reformation. Starting from case-studies of South-West Germany, Switzerland and Alsace, the essays broaden out to consider the formation of economic landscapes, the development of urban territories, and the survival of forms of serfdom throughout Germany as a whole. While issues of economic and social structure take pride of place, they are accompanied by analysis of regional mentalities and cultural identities as well. With an Introduction by Tom Brady.
Programmed cell death (PCD) is central in maintaining the life of multicellular organisms, during development as well as in healthy adulthood or in the context of disease. The best understood form of PCD is apoptosis, a caspase mediated, immunologically silent cell death that can be initiated in probably all cell types upon aging, lack of growth support, critical damage or infection. One of the key pathways of apoptosis involves mitochondrial outer membrane permeabilization (MOMP), a process tightly regulated by members of the BCL-2 family. Whereas PCD and apoptosis were used synonymously in the past, other forms of PCD have been discovered more recently, including RIPK1/3- and MLKL-dependen...