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The Hepatocyte Review
It is thirty years since the technique of high-yield preparation of isolated hepatocytes, by collagenase perfusion of the liver, was published. The original method described by Berry and Friend has undergone many minor modifications by other workers, and the two-step procedure introduced by Seglen in 1976 has become the most frequent way to prepare hepatocyte suspensions. An important development introduced by Bissell in 1973 was the use of the cells as the first step in monolayer culture. The availability of the isolated hepatocyte preparation as cells in suspension or culture has undoubtedly facilitated research on the liver. This was emphasised in our book, published (with Dr. Greg Barrit...
Gastroenterology For General Surgeons
This book fills a void in the market for specialists who are working in areas without the support of gastroenterologists. Due to a lack of local expertise, treatment decisions in the field of gastroenterology frequently have to be made by non-gastroenterologists. The book addresses this problem by providing clear instructions on the diagnosis, medical management and on-going treatment of the most common disease patterns encountered in gastroenterology. Written by leading experts in their respective fields, it offers up-to-date evidence and insights into these conditions to enable adequate decision-making and safe management of these conditions.
Molecular Staging of Cancer
An explosion of information has occurred since scientists began to define the molecular events that describe the malignant transformation and progression of cells and their development towards a life-threatening metastatic disease. The First International Congress on Molecular Staging of Cancer, held in Munich in December 2001, aimed to establish an international platform of exchange among molecular biologists, cell biologists, tumor immunologists, and clinical and surgical oncologists. This network approach should be fruitful for both clinicians and researchers. The highlighted topics included tumor-associated proteolysis, minimal residual disease, new approaches for molecular diagnosis and targeting, and the first molecular staging models. One session focused on technology transfer, opening up a new field of funding for innovative concepts. Finally, the impact of molecular staging on clinical strategies was discussed.
Biofluid Mechanics
Proceedings of the 2nd International Symposium Biofluid Mechanics and Biorheology. June 25-28, 1989, Munich
Springer-Verlag: History of a Scientific Publishing House
A chronicle written only by someone for whom the present important. Goethe, Maximen und Reflexionen The second volume of our company's history differs from the first in several ways. With a great appreciation of history, Heinz Sarkowski has impressively reconstructed the company cor- spondence, which is fortunately almost completely preserved, and made it speak. * There is an inexhaustible amount of c- respondence pertaining to the period I have taken it upon myself to cover, and working through it properly not only would have required many years, but also would have detracted from the immediacy of the account. Thus, I decided to proceed from personal experience, to describe what has happene...
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