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Basic Epithelial Ion Transport Principles and Function
This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fu...
Polyamines in Health and Nutrition
The importance of polyamines for all living cells has been recognized since spermine was discovered in human semen more than 300 years ago. Polyamine research intensified when analytical methods were developed for their determination, particularly in tissues and biological fluids. Discovering their close correlation with cancer, and that polyamine concentrations change during the cell cycle, gave reason for further research in this topic. Polyamines in Health and Nutrition concentrates on the direction of polyamine research which has the capacity to influence and benefit our health and which can explain some of the discrepancies and failures of earlier research. It is important to recognize the dietary contribution to the polyamine body pool and to investigate how the polyamine content of the diet can be changed, with the ultimate aim of using this information to improve our health.
Early Modern European Diplomacy
New Diplomatic History has turned into one of the most dynamic and innovative areas of research – especially with regard to early modern history. It has shown that diplomacy was not as homogenous as previously thought. On the contrary, it was shaped by a multitude of actors, practices and places. The handbook aims to characterise these different manifestations of diplomacy and to contextualise them within ongoing scientific debates. It brings together scholars from different disciplines and historiographical traditions. The handbook deliberately focuses on European diplomacy – although non-European areas are taken into account for future research – in order to limit the framework and ensure precise definitions of diplomacy and its manifestations. This must be the prerequisite for potential future global historical perspectives including both the non-European and the European world.
Reviews of Physiology, Biochemistry and Pharmacology 153
Offers individual discussions of cell functions as they relate to physiology, biochemistry, or pharmacology. Topics covered include molecular mechanisms in membrane polarity, pharmacological properties of cerium compounds, and recruitment of Hsp70 chaperones.
