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The Coordination Chemistry of Metalloenzymes
Assembling a program in bioinorganic chemistry that is scientifi cally relevant, well defined, and self-consistent is not an easy task. In this attempt we decided to consider zinc enzymes, copper oxidases, cytochromes and cytochrome oxidase. The choice is in part due to the great attention that the current specialized literature devotes to these topics, which are now debated among chemists, biochemists, biophysicists, etc .. We believe that hydration reactions, hydrolytic and oxidative processes have much in common from the point of view of the reaction mechanisms, the comprehension of which represents a frontier of science. For these reasons these topics have been the subject of the NATO-AS...
The Medicinal Chemist's Guide to Solving ADMET Challenges
Presented in a visual and accessible style this volume intends to provide rapid solutions to overcome the universal challenges to optimizing ADMET.
A Guide to Materials Characterization and Chemical Analysis
Written both for the novice and for the experienced scientist, this miniature encyclopedia concisely describes over one hundred materials methodologies, including evaluation, chemical analysis, and physical testing techniques. Each technique is presented in terms of its use, sample requirements, and the engineering principles behind its methodology. Real life industrial and academic applications are also described to give the reader an understanding of the significance and utilization of technique. There is also a discussion of the limitations of each technique.
Quarterly Calendar
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Iron and Copper Proteins
An Fe- and Cu-Protein Symposium was held on December 15-18, 1975 at the East West Center-University of Hawaii and was sponsored by the United States-Japan Cooperative Science Program under the auspices of the National Science Foundation and the Japan Society for the Promotion of Science. It was recognized by the organizers of the symposium that metalloproteins are very important in the field of health science and a subject worthy of discussion by experts from the United States, Japan and Europe. The meeting was restricted to Fe- and Cu-proteins but this is still a very broad subject matter and therefore, selected topics of current interest in this field were chosen. This book contains the co...
Antimalarial Agents
Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world's population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential. Beginning with a historical overview of malaria and antimalarial research, this book goes on to describe the biological aspect...
