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This publication is based on peer-reviewed manuscripts from the 2022 Conference on Current Trends in Drug Discovery, Development and Delivery (CTD4-2022) held at KL University, India. Providing a wide range of up to date topics on the latest advancements in drug design and discovery technologies, this book ensures the reader receives a good understanding of the scope of the field. Aimed at scientists, students, regulators, academics and consultants throughout the world, this book is an ideal resource for anyone interested in the state of the art in drug design and discovery.
Quality by design (QbD) is becoming an integral element of the modern pharmaceutical and chemical development approach. In this book, the future ramifications of emergent modern applications of QbD and green analytical chemistry in drug design, process analytical technologies, and bioanalytical process development instruments are discussed. It will reveal and improve the QbD principles used in bioanalysis, process development, downstream processing, and the combination of QbD and green analytical chemistry employing eco-friendly and green solvents for product development. In addition, it will provide complete information regarding applying the QbD concept and ideology to quality control and process development. The book will be beneficial to PhD research scholars, researchers, and postgraduate and undergraduate students of pharmacy and chemical sciences for understanding the concept of quality by design and green chemistry for drug design, as it illustrates the necessary inputs that are related to product quality and, ultimately, process sustainability.
This book is a valuable resource on the subject of off-pump coronary artery bypass (OPCAB) surgery, which has recently been developed as a promising technique for reducing surgical damage to patients. Because of the increasing number of older patients who are candidates for a coronary artery bypass graft (CABG) operation, less-invasive surgeries are becoming a priority all over the world. Despite some challenges, such as its technical difficulties, emerging questions, and controversies involved, OPCAB surgery in CABG is now the gold standard in Japan. This book, written by OPCAB experts, examines the procedure established and its chief benefits. Its coverage ranges from a careful evaluation ...
This path-breaking book provides a convincing argument for the importance of children's home languages and the benefits of dual- and multi-language learning. A new classroom practice known as Linguistically Appropriate Practice (LAP) offers guidance for those working with young children who arrive in childcare centres and schools with little or no proficiency in the classroom language. Linguistically Appropriate Practice details over fifty classroom activities that can be adapted to match both the developmental level of the children and the classroom curriculum. Intended for childcare staff, health care providers, settlement workers, speech and language pathologists, kindergarten and primary grade teachers, family resource workers, and literacy specialists, this book is an essential resource for preparing young children for the complex communication and literacy demands of the twenty-first century.
This book describes the different aspects of ischemic heart disease, one of the leading causes of death in industrialized countries, and whose growing prevalence represents a major challenge in terms of short- and long-term management and surveillance. This volume offers a comprehensive discussion of the state-of-the-art diagnostic imaging options, of disease risk stratification, selection of candidates for surgical intervention, percutaneous revascularitation, mechanical assist devices implantation. Recently, the morbidity and mortality of ischaemic heart disease have substantially improved because of the progress in therapeutic strategies, represented by the dramatic evolution of percutane...
Secondary Metabolites and Biotherapeutics presents the latest biotechnological advancements in the production of target secondary metabolites for medicinal use, including topics such as transcriptomics, nanotechnology, gene editing tools like CRISPR/CAS, secondary metabolites source and production.? Secondary metabolites derived from plants as a response to stress have always played a vital role in the pharmaceutical industry to produce medicines. However, their limited production in plants have always raised concerns for large-scale production. With the advancement of modern biotechnology, researchers around the globe are now able to engineer plants with specific chemical compositions.This ...
Artificial Intelligence (AI) and the Internet of Things (IoT) are growing rapidly in today’s business world. In today's era, 25 billion devices, including machines, sensors, and cameras, are connected and continue to grow steadily. It is assumed that in 2025, 41.6 billion IoT devices will be connected, generating around 79.4 zettabytes of data. IoT and AI are intersecting in various scenarios. IoT-enabled devices are generating a huge amount of data, and with the help of AI, this data is used to build various intelligent models. These intelligent models are helpful in our daily lives and make the world smarter. Artificial Intelligence in Cyber Physical Systems: Principles and Applications addresses issues related to system safety, security, reliability, and deployment strategies in healthcare, military, transportation, energy, infrastructure, smart homes, and smart cities.
Fully revised and updated, this text provides an authoritative account of all aspects of perioperative care for surgical patients.
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.