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Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders
Compared with other disease areas, central nervous system (CNS) disorders have had the highest failure rate for new compounds in advanced clinical trials. Most CNS drugs fail because of efficacy, and the core issue underlying these problems is a poor understanding of disease biology. Concern about the poor productivity in neuroscience drug development has gained intensity over the past decade, amplified by a retraction in investment from the pharmaceutical industry. This retreat by industry has been fueled by the high failure rate of compounds in advanced clinical trials for nervous system disorders. In response to the de-emphasis of CNS disorders in therapeutic development relative to other...
Official Register
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Annual Reports in Medicinal Chemistry
This serial continues to combine regular updates of significant research in medicinal chemistry with emerging research in biological science destined to impact the discovery and development of new medicinal agents.
PRICAI 2000 Topics in Artificial Intelligence
PRICAI 2000, held in Melbourne, Australia, is the sixth Pacific Rim Interna tional Conference on Artificial Intelligence and is the successor to the five earlier PRICAIs held in Nagoya (Japan), Seoul (Korea), Beijing (China), Cairns (Aus tralia) and Singapore in the years 1990, 1992, 1994, 1996 and 1998 respectively. PRICAI is the leading conference in the Pacific Rim region for the presenta tion of research in Artificial Intelligence, including its applications to problems of social and economic importance. The objectives of PRICAI are: To provide a forum for the introduction and discussion of new research results, concepts and technologies; To provide practising engineers with exposure to ...
Semiconductor Nanowires
A timely reference from leading experts on semiconductor nanowires and their applications.
Handbook of Dual Diagnosis
This handbook addresses behavior problems and mental health disorders in persons with intellectual disabilities. It provides an overview of the history of dual diagnosis and related theories, ethics, diagnostic systems, mental health disorders, and challenging behaviors. The handbook examines general clinical issues, such as the effects of cognitive performance on the choice of assessment and treatment methods, service delivery systems, education models, risk factors, functional assessment, and structured interviews. Chapters provide a much-needed reference for practitioners and practitioners in training. The applied focus of the book continues with assessment/diagnosis sections of mental he...
Intelligent Systems and Applications
This book presents the proceedings of the International Computer Symposium 2014 (ICS 2014), held at Tunghai University, Taichung, Taiwan in December. ICS is a biennial symposium founded in 1973 and offers a platform for researchers, educators and professionals to exchange their discoveries and practices, to share research experiences and to discuss potential new trends in the ICT industry. Topics covered in the ICS 2014 workshops include: algorithms and computation theory; artificial intelligence and fuzzy systems; computer architecture, embedded systems, SoC and VLSI/EDA; cryptography and information security; databases, data mining, big data and information retrieval; mobile computing, wireless communications and vehicular technologies; software engineering and programming languages; healthcare and bioinformatics, among others. There was also a workshop on information technology innovation, industrial application and the Internet of Things. ICS is one of Taiwan's most prestigious international IT symposiums, and this book will be of interest to all those involved in the world of information technology.
Silicon and Silicide Nanowires
Nanoscale materials are showing great promise in various electronic, optoelectronic, and energy applications. Silicon (Si) has especially captured great attention as the leading material for microelectronic and nanoscale device applications. Recently, various silicides have garnered special attention for their pivotal role in Si device engineering
