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Bioactive Peptides in Drug Discovery and Design
As in previous editions, the focus in ESSENTIAL MATHEMATICS with APPLICATIONS remains on the Aufmann Interactive Method (AIM). Students are encouraged to be active participants in the classroom and in their own studies as they work through the How To examples and the paired Examples and You Try It problems. Student engagement is crucial to success. Presenting students with worked examples, and then providing them with the opportunity to immediately solve similar problems, helps them build their confidence and eventually master the concepts. Simplicity is key in the organization of this edition, as in all other editions. All lessons, exercise sets, tests, and supplements are organized around ...
Drug Metabolism
With its roots in the last century and currently exploiting the technology of today, the science of drug metabolism has made significant contributions to our understanding of chemico-biological interactions. This book reviews past successes and failures within the science and attempts to predict new directions. Each of the chapters of this book deals with an aspect of xenobiotic metabolism which has featured prominently in the development of the discipline. The volume is testimony to the breadth and depth of research into xenobiotic metabolism and covers the chemistry and enzymology of xenobiotic metabolism, enzyme modeling and structure activity relationships, pharmacokinetics, the use of r...
Human Genome Analysis
The rationale for co-ordinated activities related to human genome analysis is based on its potential contribution to the understanding of the processes underlying human disease, hence to improve diagnostics, treatment and eventually disease prevention. The basic idea on how best to meet this objective at a European level was through the collective improvement of research infrastructure, broader availability of resources and co-operation of leading research groups in Europe. The emphasis of the European programmes was placed on the provision of an adequate research infrastructure, including resource centres, to the improvement in the mapping facilities and information management. In this context, a paradigm of successful international collaboration was the European Human Genetic Linkage Mapping Project (EUROGEM), and the Single Chromosome Workshops (SCWs), monitored by the Human Genome Organisation (HUGO). This book contains the final reports of all 41 research projects funded under the BIOMED 1 programme during the period 1993 to 1997.
Dopamine Receptor Subtypes
Multiple subtypes of dopamine receptors exist in the brain. This volume reviews the characteristics of D-1, D-2, D-3 and D-4 receptors and describes the current concepts of their involvement in motor disorders and in the control of schizophrenia. Readers: the book will be of great interest to professionals in pharmacology, medicinal chemistry, neuroscience, cell biology and therapeutic applications in clinical medicine as antipsychotics, anti-Parkinson's disease and related areas.
EURO-QUAL
The benefits for the professional working within a quality culture are manifold, but even more important, the patient is the final arbiter of quality care. Therefore patient centred aspects of treatment are focused upon in this manual. A quality manual intended for European use has to respect the national regulations and European diversity, and therefore needs to be flexible. The EOQM has been structured according to the treatment of the individual patient, which is what all professionals have in common, and which also is the most important target for quality improvement in orthodontic practice. The EOQM is primarily designed as a stimulus for the orthodontic professional to assess and impro...
EUCAMBIS
EUCAMBIS was established under BIOMED I in 1994 as an interdisciplinary consortium aiming to advance our understanding of the molecular and cellular bases of ageing of immunosenescence. The project sought to draw together scientists and clinicians from diverse fields including immunology, molecular biology, cell and tumour biology, geriatrics, endocrinology and transplantation biology in order to investigate the impact of ageing on immune responses. The papers collected in this volume illustrate the diversity of the work carried out by the members of EUCAMBIS during its three-and-a-half year existence. This introductory chapter attempts to summarize the results of some of the EUCAMBIS collaborations, with emphasis on the "workshop" approach which was aimed at analysing the expression of "growth arrest" genes in ageing human T lymphocytes.
The Neuronal Ceroid Lipofuscinoses (Batten Disease)
The European Concerted Action on the "Neuronal Ceroid Lipofuscinoses (NCL)", probably the most frequent group of progressive neurodegenerative disorders in children, has been the subject of a 3-year European Concerted Action (ECA-"NCL"), within the Biomed 2 programme, listed among "Rare diseases". The NCL are a lysosomal disease which have recently been confirmed by important genetic studies on the NCL which revealed a diversity of at least 8 gene loci related to this group of diseases. ECA-"NCL" represents a multi-national, multi-disciplinary network of researchers on the NCL which have provided new data on this group of diseases. In this book, clinical features, neuroradiological and elect...
Frontiers in Head and Neck Trauma
Responding to the trend toward sustainable living, "Recipes and Tips for Sustainable Living" helps you make delicious food using natural ingredients. Inside this lushly illustrated volume, you'll find: Tips and techniques to grow and harvest natural, organic foods in and around your home. More than 80 mouth-watering recipes for cooking those ingredients. Tips on preservation and storage of your harvest. Health benefits of natural, organic ingredients. Chapters cover: Gardening - Heirloom gardening, container gardening, herbs and preserving. Beyond the Garden - Foraging, beekeeping, poultry and eggs. Wood and Water - Venison, wild turkey, duck, quail, small game, seafood and fish.
Enzymatic Mechanisms
The market-leading text for the Elementary School Music Methods course, INTEGRATING MUSIC INTO THE ELEMENTARY CLASSROOM was the first to emphasize the theme of integrating music throughout the school day. Anderson and Lawrence show future educators how to make music an effective part of the entire elementary curriculum. The text introduces songs, instruments, sources of age-appropriate music, and methods of making music in a multicultural environment -- making it perfect for students with no prior knowledge of music fundamentals. With easy techniques for teaching young children how to sing, play instruments, move to music, create music, listen to music, and understand music, this text relates music to all subject areas. Notably, the authors provide sample lesson plans for kindergarten through sixth grade, along with more than 150 songs from different cultures and historical periods. Available with InfoTrac® Student Collections http://gocengage.com/infotrac.
Aging in Europe
Human aging is perhaps the most complex and important subject that will be facing science and societies in the next century. Persons seem to be living longer and remaining more active than their parents and grandparents. This is leading to social and demographic shifts that must be accommodated by society. On the other hand it presents perplexing questions about the underlying processes and determinants of healthy aging. This book gives a design for research that will increase our understanding of the factors that influence healthy aging and can lead to improvements in reducing the levels of disability in the population. It's focus is on biobehavioural and psychological factors contributing ...
