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Dosimetry for Radiopharmaceutical Therapy
In this publication the basic principles of radiation physics, imaging and non-imaging instrumentation used, measurement of the administered activity, calibration procedures and methods for obtaining quantitative information on the biodistribution of the radioactive drug to be used with radioisotopes relevant to therapy are specified. It also describes methods for segmentation and registration of images acquired at different time points, strategies for fitting and integration of activity measurements over the time of treatment, absorbed dose calculations and derived dosimetric indexes with methods to estimate the overall uncertainty of different radionuclide therapies. The aim of this book is to fill the existing gaps in education and training of medical physicists on methods for patient-specific dosimetry. The overall objective of this book is to highlight the tools and methodologies to assure that radiopharmaceutical therapy is implemented through a dosimetry-guided individualized treatment approach.
Targeted Radionuclide Tumor Therapy
The last three decades have provided opportunities to explore the potential of treating malignant diseases with antibodies or other targeting molecules labelled with nuclides. While considerable advances have been reported, there is still a signi- cant amount of work left to accomplish before our ambitions can be achieved. It now seems timely to review the accomplishments achieved to date and to clarify the challenges that remain. The choice of radionuclide, the conjugation p- cedure employed, and the selection of suitable targets were early issues that were faced by our field that still persist, however we can now tackle these obstacles with significantly better insight. The expanding array...
Therapeutic Nuclear Medicine
The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.
Advances in Molecular Nanotechnology Research and Application: 2012 Edition
Advances in Molecular Nanotechnology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Molecular Nanotechnology. The editors have built Advances in Molecular Nanotechnology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Molecular Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Molecular Nanotechnology Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Radiopharmaceutical Therapy
This book covers foundational topics in the emerging field of radiopharmaceutical therapy. It is divided into three sections: fundamentals, deeper dives, and special topics. In the first section, the authors examine the field from a bird’s-eye view, covering topics including the history of radiopharmaceutical therapy, the radiobiology of radiopharmaceutical therapy, and the radiopharmaceutical chemistry of both metallic and non-metallic radionuclides. The second section provides a more in-depth look at specific radiotherapeutics. Chapters include broader discussions of the different platforms for radiopharmaceutical therapy as well as more focused case studies covering individual radiotherapeutics. The third and final section explores a number of areas for further study, including medical physics, artificial intelligence, in vivo pretargeting, theranostic imaging, and the regulatory review process for radiotherapeutics. This book is the first of its kind and is useful for a broad audience of scientists, researchers, physicians, and students across a range of fields, including biochemistry, cancer biology, nuclear medicine, radiology, and radiation oncology.
Methods and Applications of Artificial Intelligence
Arti?cial intelligence has attracted a renewed interest from distinguished sci- tists and has again raised new, more realistic this time, expectations for future advances regarding the development of theories, models and techniques and the use of them in applications pervading many areas of our daily life. The borders of human-level intelligence are still very far away and possibly unknown. Nev- theless, recent scienti?c work inspires us to work even harder in our exploration of the unknown lands of intelligence. This volume contains papers selected for presentation at the 3rd Hellenic Conference on Arti?cial Intelligence (SETN 2004), the o?cial meeting of the Hellenic Society for Arti?cial ...
Advances in Meteorology, Climatology and Atmospheric Physics
This book essentially comprises the proceedings of the 11th International Conference of Meteorology, Climatology and Atmospheric Physics (COMECAP 2012) that is held in Athens from 30 May to 1 June 2012. The Conference addresses researchers, professionals and students interested in the following topics: Agricultural Meteorology and Climatology, Air Quality, Applied Meteorology and Climatology, Applications of Meteorology in the Energy Sector, Atmospheric Physics and Chemistry, Atmospheric Radiation, Atmospheric Boundary Layer, Biometeorology and Bioclimatology, Climate Dynamics, Climatic Changes, Cloud Physics, Dynamic and Synoptic Μeteorology, Extreme Events, Hydrology and Hydrometeorology, Mesoscale Meteorology, Micrometeorology/Urban Microclimate, Remote Sensing/ Satellite Meteorology and Climatology, Weather Analysis and Forecasting. The book includes all papers that have been accepted for presentation at the conference.
Indicators and Reagents—Advances in Research and Application: 2012 Edition
Indicators and Reagents—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Indicators and Reagents. The editors have built Indicators and Reagents—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Indicators and Reagents in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Indicators and Reagents—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Nanochemistry for Chemistry Educators
For the first time, this book sets out ways to teach the science of nanochemistry at a level suitable for pre-service and in-service teachers in middle and secondary school. The authors draw upon peer-reviewed science education literature for experiments, activities, educational research, and methods of teaching the subject. The book starts with an overview of chemical nanotechnology, including definition of the basic concepts in nanoscience, properties, types of nanostructured materials, synthesis, characterization, and applications. It includes examples of how nanochemistry impacts our daily lives. This theoretical background is an address for teachers even if they do not have enough infor...
Handbook of Materials for Nanomedicine
The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.
