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Since the turn of the twenty-first century, applications of ion mobility spectrometry (IMS) have diversified, expanding their utility in the military and security spheres and entering the realms of clinical practice and pharmaceutical exploration. Updated and expanded, the third edition of Ion Mobility Spectrometry begins with a comprehensive discussion of the fundamental theory and practice of IMS. Divided into four sections—Overview, Technology, Fundamentals, and Applications—the authors treat innovations and advances in all aspects of IMS in a fresh, thorough, and revised format. Features: Introduces the definitions, theory, and practice of IMS and summarizes its history from the begi...
The detection of hidden explosives has become an issue of utmost importance in recent years. While terrorism is not new to the international community, recent terrorist attacks have raised the issue of detection of explosives and have generated a great demand for rapid, sensitive and reliable methods for detecting hidden explosives. Counterterrorist Detection Techniques of Explosives covers recent advances in this area of research including vapor and trace detection techniques (chemiluminescence, mass spectrometry, ion mobility spectrometry, electrochemical methods and micromechanical sensors, such as microcantilevers) and bulk detection techniques (neutron techniques, nuclear quadrupole res...
Detection and quantification of trace chemicals is a major thrust of analytical chemistry. In recent years much effort has been spent developing detection systems for priority pollutants. Less mature are the detections of substances of interest to law enforcement and security personnel:in particular explosives. This volume will discuss the detection of these, not only setting out the theoretical fundamentals, but also emphasizing the remarkable developments in the last decade. Terrorist events—airplanes blown out of the sky (PanAm 103 over Lockerbie) and attacks on U.S. and European cities (Trade Center in New York and the Murrah Federal Building in Oklahoma City, railways in London and Ma...
Key Developments for Faster, More Precise Detection Capabilities Driven by the demand for the rapid and advanced detection of explosives, chemical and biological warfare agents, and narcotics, ion mobility spectrometry (IMS) undergone significant refinements in technology, computational capabilities, and understanding of the principles of gas phase
The different LC-MS techniques available today were developed to suit specific analytical needs and the application range covered by each one is wide, but still limited. GC amenable compounds can be all analyzed with a single GC-MS system whereas HPLC applications call for specific LC-MS instrumental arrangements. ESI, APCI, APPI, and EI are ionization techniques that can be combined with different analyzers, in single or tandem configuration, to create the ultimate system for a certain application. Once approaching LC-MS for a specific need, the fast technical evolution and the variegated commercial offer can induce confusion in the potential user.The role of this book is to enlighten the s...
This thesis addresses the evolving field of measurement science, specifically that of mass spectrometry (MS) and ion mobility spectrometry (IMS) based techniques. It focuses on the design, construction and implementation of low-cost, easy-to-manufacture measurement tools that are used in modern settings such as airport security screening. Advances in these technologies often involve minimal performance enhancement at ever-increasing cost, which in turn limits accessibility to versatile measurement tools. This problem is addressed using desktop 3D printers along with widely available materials for the production of novel ion lenses and an IMS instrument with a performance comparable to that of many commercial systems. Baird ́s findings are a source of inspiration for scientists exploring this emerging field./div
Contains an outline of the principles and characteristics of relevant instrumental techniques, provides an overview of various aspects of direct additive analysis by focusing on an array of applications in R ampD, production, quality control, and technical service.
Bioavailability refers to the extent to which humans and ecological receptors are exposed to contaminants in soil or sediment. The concept of bioavailability has recently piqued the interest of the hazardous waste industry as an important consideration in deciding how much waste to clean up. The rationale is that if contaminants in soil and sediment are not bioavailable, then more contaminant mass can be left in place without creating additional risk. A new NRC report notes that the potential for the consideration of bioavailability to influence decision-making is greatest where certain chemical, environmental, and regulatory factors align. The current use of bioavailability in risk assessment and hazardous waste cleanup regulations is demystified, and acceptable tools and models for bioavailability assessment are discussed and ranked according to seven criteria. Finally, the intimate link between bioavailability and bioremediation is explored. The report concludes with suggestions for moving bioavailability forward in the regulatory arena for both soil and sediment cleanup.