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Encoding Visual Features by Parallel Ganglion Cell Initiated Pathways in the Healthy, Diseased and Artificial Retina
Photons are sensed by retinal photoreceptors whose matrix-like distribution underlies the transformation of illumination patterns of the visual scene into photoreceptor activity patterns in a visuotopic fashion. Activity of neighboring photoreceptors then are compared by secondary bipolar cells to decipher information regarding luminosity- and color-contrast. Bipolar cells achieve this by comparing signals received directly from their center receptive field with those come from spatially offset surrounding receptive field areas mediated by inhibitory, sign-inverting horizontal cells. This information is ultimately sent to retinal ganglion cells, the output neurons of the retina. In addition ...
Los Alamos Science
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Big Data Is Not a Monolith
Perspectives on the varied challenges posed by big data for health, science, law, commerce, and politics. Big data is ubiquitous but heterogeneous. Big data can be used to tally clicks and traffic on web pages, find patterns in stock trades, track consumer preferences, identify linguistic correlations in large corpuses of texts. This book examines big data not as an undifferentiated whole but contextually, investigating the varied challenges posed by big data for health, science, law, commerce, and politics. Taken together, the chapters reveal a complex set of problems, practices, and policies. The advent of big data methodologies has challenged the theory-driven approach to scientific knowl...
Computation and Neural Systems
Computational neuroscience is best defined by its focus on understanding the nervous systems as a computational device rather than by a particular experimental technique. Accordinlgy, while the majority of the papers in this book describe analysis and modeling efforts, other papers describe the results of new biological experiments explicitly placed in the context of computational issues. The distribution of subjects in Computation and Neural Systems reflects the current state of the field. In addition to the scientific results presented here, numerous papers also describe the ongoing technical developments that are critical for the continued growth of computational neuroscience. Computation and Neural Systems includes papers presented at the First Annual Computation and Neural Systems meeting held in San Francisco, CA, July 26--29, 1992.
Computational Neuroscience
This volume includes papers presented at the Fifth Annual Computational Neurosci ence meeting (CNS*96) held in Boston, Massachusetts, July 14 - 17, 1996. This collection includes 148 of the 234 papers presented at the meeting. Acceptance for mceting presenta tion was based on the peer review of preliminary papers originally submitted in May of 1996. The papers in this volume represent final versions of this work submitted in January of 1997. As represented by this volume, computational neuroscience continues to expand in quality, size and breadth of focus as increasing numbers of neuroscientists are taking a computational approach to understanding nervous system function. Defining computa tional neuroscience as the exploration of how brains compute, it is clear that there is al most no subject or area of modern neuroscience research that is not appropriate for computational studies. The CNS meetings as well as this volume reflect this scope and di versity.
Functional Informatics in Drug Discovery
Integrating various technologies with informational systems provides vast improvements to the overall research and development that occur in the biopharmaceutical industry. One of the first books to explore this area, Functional Informatics in Drug Discovery examines all aspects of technology integration and information flow in a biopharmaceutical
Advances in Visual Computing
This book constitutes the refereed proceedings of the 13th International Symposium on Visual Computing, ISVC 2018, held in Las Vegas, NV, USA in November 2018. The total of 66 papers presented in this volume was carefully reviewed and selected from 91 submissions. The papers are organized in topical sections named: ST: computational bioimaging; computer graphics; visual surveillance; pattern recognition; vitrual reality; deep learning; motion and tracking; visualization; object detection and recognition; applications; segmentation; and ST: intelligent transportation systems.
Data Analytics and Machine Learning for Integrated Corridor Management
In an era defined by rapid urbanization and ever-increasing mobility demands, effective transportation management is paramount. This book takes readers on a journey through the intricate web of contemporary transportation systems, offering unparalleled insights into the strategies, technologies, and methodologies shaping the movement of people and goods in urban landscapes. From the fundamental principles of traffic signal dynamics to the cutting-edge applications of machine learning, each chapter of this comprehensive guide unveils essential aspects of modern transportation management systems. Chapter by chapter, readers are immersed in the complexities of traffic signal coordination, corri...
Nonlinear Dynamical Analysis Of The Eeg: Proceedings Of The 2nd Annual Conference
This volume contains papers, contributed by scientists from a wide variety of disciplines, on the application of nonlinear dynamics (chaos theory) in the study of brain function.
The Pentagon's Brain
Discover the definitive history of DARPA, the Defense Advanced Research Project Agency, in this Pulitzer Prize finalist from the author of the New York Times bestseller Area 51. No one has ever written the history of the Defense Department's most secret, most powerful, and most controversial military science R&D agency. In the first-ever history about the organization, New York Times bestselling author Annie Jacobsen draws on inside sources, exclusive interviews, private documents, and declassified memos to paint a picture of DARPA, or "the Pentagon's brain," from its Cold War inception in 1958 to the present. This is the book on DARPA -- a compelling narrative about this clandestine intersection of science and the American military and the often frightening results.
