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Culture Negative Orthopedic Biofilm Infections
During the recent transition between acute diseases caused by swarms of single planktonic bacteria, and chronic infections caused by bacteria growing in slime-enclosed biofilms, a general clinical consensus has emerged that pathologies with bacterial etiologies are frequently culture negative. Because biofilm infections now affect 17 million Americans per year (killing approximately 450,000), the suggestion that these common and lethal infections regularly go unnoticed by the only FDA-approved method for their detection and characterization is a matter of urgent concern. Biologically, we would expect that planktonic bacterial cells would colonize any new surface, including the surface of an ...
The Retroviridae
The books in this acclaimed series are the most detailed, up-to-date accounts of the field available. Volume 3 explores the oncogenic potential shared by retroviruses of different species, the widespread presence of retrovirues in nature, and the role of retroviruses in normal development and pathogenesis.
The Pangenome
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, p...
PCR Protocols
The correct procedures you need for frustration-free PCR methods and applications are contained in this complete, step-by-step, clearly written, inexpensive manual. - Avoid contamination--with specific instructions on setting up your lab - Avoid cumbersome molecular biological techniques - Discover new applications
Pediatric Otolaryngology
Preceded by: Pediatric otolaryngology / [edited by] Charles D. Bluestone ... [et al.]. 4th ed. c2003.
Evidence-based Otitis Media
Evidence-Based Otitis Media offers one-stop shopping for the best current evidence to guide management decisions at the individual, organizational, and societal levels. This text details the importance of evidence-based data in interpreting the ever-enlarging body of literature on otitis media. The editors have assembled an impressive group of experts on all aspects of otitis media and addressed comprehensively many issues related to methodology, clinical management, and consequences of this disease. The eight chapters comprising the methodology section provide the necessary background and detail to allow physicians and other health professionals to understand and appreciate the value of evi...
Ballenger's Otorhinolaryngology
This comprehensive compendium of current knowledge in the fields of otology/neurotology, rhinology, facial plastic and reconstructive surgery, paediatric otorhinolaryngology, head and neck surgery and bronchoesophagology features sections on facial plastic, reconstructive surgery and paediatrics. The content reflects the central responsibility of the otorhinolaryngologist in treating patients with diseases affecting the senses of smell, taste and balance. Also encompassed in this section are treatments for disorders of human communication affecting hearing, voice, speech and language.
Medical Virology 9
It would have been difficult at the beginning of the 80's to have predicted that by the end of the decade, Medical Virology would have become one of the most important topics in the area of both basic and clinical research. Although we were expecting a progressive increase in awareness of the role played by viruses in different diseases, we did not expect the outbreak of a fatal disease that was going to shake the roots of our society. The appearance of the human immunodeficiency virus (HIV-1) in the early 80's, has prompted a unique re search impetus in the area of Medical Virology. The knowledge that we are gaining in our attempt to understand the biology of HIV-1 and the immuno logical re...
Biofilm-based Healthcare-associated Infections
The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.
Otitis Media
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