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Metabolic Basis of Obesity
The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growi...
Pediatric Inflammatory Bowel Disease
Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figur...
Next-Generation Nutritional Biomarkers to Guide Better Health Care
There are only a few areas in human nutrition and metabolism where biomarkers are routinely used to predict health and functional outcome. For instance, of the four major nutritional deficiencies, only iron deficiency can be precisely diagnosed by employing biomarkers. They therefore play a limited role in research and decision making, and intervention strategies are still mostly targeted at the population level. What is needed at this stage are biomarkers that are predictive of later functional health and that stay stable from infancy to childhood and adult health. Moreover, individual variability must be considered, taking into account the complexity of foods, lifestyle, and metabolic proc...
The Importance of Immunonutrition
A pediatric perspective Our daily food intake not only provides the calories and the macro- and micronutrients necessary for survival - nutrients also have a tremendous potential to modulate the actions of the immune system, a fact which has a significant impact on public health and clinical practice. This book presents the latest findings on how nutrient status can modulate immunity and improve health conditions in pediatric patients. Divided into three parts, it covers major aspects of the interplay between nutrients and the regulation of immunity and inflammatory processes. Part one deals with the pharmaceutical value of specific amino acids (arginine and glutamine) and hormones for addressing immune disorders and infant development. The second part revolves around gut function and immunity, and the right balance of probiotics. The final part explores the role of lipid mediators and how their types and proportions can tip the balance in favor of health and disease.
Future Humans
"Evolutionary biologist Scott Solomon draws on the explosion of discoveries in recent years to examine the future evolution of our species. Combining knowledge of our past with current trends, Solomon offers convincing evidence that evolutionary forces still affect us today. But how will modernization--including longer lifespans, changing diets, global travel, and widespread use of medicine and contraceptives--affect our evolutionary future?" --publisher description.
Dietary Fiber in Health and Disease
This volume carries the proceedings of the Vahouny Fiber Symposium, which took place in Washington DC, in March of 1996. George V. Vahouny pioneered this conference, which was conceived as a means of exchanging information on the latest advances in fiber research. The conference was renamed in George Vahouny's honor after his untimely death. In this volume we have included the reminiscences of Prof. A.R.P. Walker, one of the pioneers in the field, and discussion of the epidemiological findings relating dietary fiber to heart disease, cancer, and gastrointestinal disease. As the overall definition of fiber has broadened we have included for discussion other aspects of carbohydrate chem istry ...
Examining Special Nutritional Requirements in Disease States
The amount of nutrients required by an individual is determined by a number of physiological processes, including absorption, metabolism, stability, and bio-activation. These processes determine nutrient needs and provide variations in requirements in the population. All have modifiers and sensitizers, such as sex, genetics, pregnancy, age, pharmaceuticals, toxins, food matrix, and epigenetics. Disease can also be a major modifier of these processes. In April 2018, the National Academies of Science, Engineering and Medicine convened a workshop in order to explore the evidence for special nutritional requirements in disease states and the medical conditions that cannot be met with a normal diet. Participants explored the impact a disease state can have on nutrient metabolism and nutritional status, and attempted to close informational gaps. This publication summarizes the presentations and discussions from the workshop.
Help Yourself
More than 125 gut-healthy recipes, plus advice and strategies to relieve inflammation-induced symptoms such as fatigue, weight gain, mood swings, and chronic pain
Microbiome Engineering
This reference book compiles the latest techniques and applications of microbiome engineering. Microbial communities interact dynamically with their hosts, creating a considerable impact on the host and their ecosystem. This book introduces readers to microbiomes and microbiome engineering. It covers topics like omics tools in microbial research, strategies to engineer human microbiomes, the application of synthetic biology to build smart microbes, and the future of microbiome engineering. It includes the application of microbiome engineering in improving human health, livestock, and agricultural productivity. The book is intended for researchers and students in the fields of microbiology and biotechnology.
