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Gene Therapy is expected to revolutionize the practice of medicine at the turn of the third Millennium. Therapeutic/prophylactic benefits should arise from both gene transfer and gene repair/inactivation protocols devised for patient's somatic cells. Gene expression cassettes, designed for the production of therapeutic proteins and non-coding RNA, are thus experimented together with emerging gene repair/inactivation techniques on a variety of inherited, acquired and infectious/parasitic diseases, including complex neuro-degenerative processes. This book presents a collection of chapters on the main aspects of Gene Therapy, some of which have already been treated in the past, and updates and ...
Examining the relationship between trade and labour regulation in light of the pressing need to promote sustainable development, Tonia Novitz interrogates how international legal architecture could be reformed so that no one in the world of work gets left behind. She highlights the dangers of pursuing labour and environmental issues on parallel tracks without recognising how they interact, ultimately arguing for the crafting of the content and application of trade rules through participatory processes, which involve the inclusive representation of all sectors of the labour market and all parts of the world.
Wood-pastures are important elements of European cultural identity and have an exceptional ecological value, yet they are in decline all over Europe. The structure of wood-pastures is strongly influenced by grazing and multiple other land uses and by local and regional environmental conditions. This book examines the diverse expressions of wood-pastures across Europe. It provides a new perspective, using a social-ecological framework to explore social and ecological values, governing institutions, threats and conservation approaches. It explores the major drivers of decline, which are shown to be related to accelerated cultural, institutional and developmental changes occurring across Europe over the past century. Case studies are included from North-Western, Southern, and Eastern Europe. Written by renowned scholars and conservationists, the book contributes to developing better, locally adapted conservation policies and management approaches for wood-pastures.
Foodborne Diseases: Case Studies of Outbreaks in the Agri-Food Industries defines the context of foodborne disease across a range of food sectors. It provides insight into the causes and management of outbreaks along with practical lessons about foodborne disease prevention strategies relevant to stakeholders throughout the food supply chain. Indiv
This two-volume set, LNCS 13163-13164, constitutes the refereed proceedings of the 7th International Conference on Machine Learning, Optimization, and Data Science, LOD 2021, together with the first edition of the Symposium on Artificial Intelligence and Neuroscience, ACAIN 2021. The total of 86 full papers presented in this two-volume post-conference proceedings set was carefully reviewed and selected from 215 submissions. These research articles were written by leading scientists in the fields of machine learning, artificial intelligence, reinforcement learning, computational optimization, neuroscience, and data science presenting a substantial array of ideas, technologies, algorithms, methods, and applications.