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The triumphs of recent biology - understanding hereditary disease, the modern theory of evolution - are all thanks to the fruit fly, the guinea pig, the zebra fish and a handful of other organisms, which have helped us unravel one of life's greatest mysteries - inheritance. Jim Endersby traces his story from Darwin hand-pollinating passion flowers in his back garden in an effort to find out whether his decision to marry his cousin had harmed their children, to today's high-tech laboratories, full of shoals of shimmering zebra fish, whose bodies are transparent until they are mature, allowing scientists to watch every step as a single fertilised cell multiples to become millions of specialised cells that make up a new fish. Each story has - piece by piece - revealed how DNA determines the characteristics of the adult organism. Not every organism was as cooperative as the fruit fly or zebra fish, some provided scientists with misleading answers or encouraged them to ask the wrong questions.
The politics of the twenty-first century is marked by dissent, tumult and calls for radical change, whether through food riots, anti-war protests, anti-government tirades, anti-blasphemy marches, anti-austerity demonstrations, anti-authoritarian movements and anti-capitalist occupations. Interestingly, contemporary political protests are borne of both the Right and Left and are staged in both the Global North and South. Globally, different instances of protest have drawn attention to the deep fissures which challenge the idea of globalisation as a force for peace. Given the diversity of these protests, it is necessary to examine the particular nature of grievances, the sort of change which i...
Myelin: Biology and Chemistry provides in-depth reviews and discussions regarding recent findings in the biology and chemistry of myelin. Topics are interdisciplinary and carry readers from the cellular level to that of the gene. Research in demyelinating diseases (naturally occurring and experimentally produced) is described and emphasizes autoimmune and virally induced mechanisms. Advances in molecular biology, such as those that provide details of the structures of the major myelin proteins, demonstrate the control of their synthesis, and explore the mutations within their genes that disrupt the process of myelination, are discussed in depth. Myelin: Biology and Chemistry will be an important addition to the libraries of molecular biologists, biochemists, cell biologists, physical chemists, immunologists, virologists, and pathologists involved in the study of myelin.
Biology of Methylotrophs introduces the reader to the study of methylotrophs - microorganisms that use reduced one-carbon compounds for growth. The book is divided into five parts. Part I covers the taxonomy, morphology, and ultrastructure of methylotrophic bacteria. Part II discusses the processes involved in their growth and metabolism. Part III talks about the possible applications of methylotrophs and their enzymes in industrial fields as well as chemistry. Part IV deals with the molecular genetics and the gene expression of methylotrophs, and Part V deals with their habitat and role in the environment. The text is recommended for microbiologists who would like to be acquainted with the subject or make further studies about methylotrophs.
The handbook A History of Science in The Netherlands aims to correct this situation by providing a chronological and thematic survey of the field from the 16th century to the present, essays on selected aspects of science in the Netherlands, and reference biographies of about 65 important Dutch scientists.
The Carbohydrate Bioengineering Meeting held in Elsinore, Denmark, April 23-26, 1995, gathered 230 scientists, mostly from Europe, with interest in carbohydrate analysis and structure; carbohydrates in medicine and glycopathology; structure, function, application, and protein engineering of carbohydrate active enzymes; oligo- and polysaccharides of industrial interest; and production of carbohydrate containing new materials.The first chapters address glycoconjugates as modulatory and recognition molecules, structure determination using NMR and mass spectrometry, and microdialysis-chip enzyme-based sensors. Active site mutations coupled with crystal structures and synthetic substrate analogue interactions as well as new three-dimensional structures and binding domains for biotechnological applications are included in the chapters. Carbohydrate active enzymes turned out to be a predominant topic.The rapid development in glycobiology and glycotechnology has resulted in an enormous increase in our knowledge on the structure conversion, and application of carbohydrates in industry and medicine.
This latest volume addresses the contemporary issues related to recombination in filamentous fungi, EST data mining, fungal intervening sequences, gene silencing, DNA damage response in filamentous fungi, cfp genes of Neurospora, developmental gene sequences, site-specific recombination, heterologous gene expression, hybridization and microarray technology to enumerate biomass. This volume also analyse the current knowledge in the area of hydrophobins and genetic regulation of carotenoid biosynthesis. Over fifty world renowned scientist from both industry and academics provided in-depth information in the field of fungal genes and genomics.