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Genomic Applications in Pathology
The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases. As a result, a plethora of clinical genomic applications have been implemented in diagnostic pathology laboratories, and the ap...
Shattered Innocence
This guidebook is geared toward mental health professionals working with women who have been victims of sexual abuse. It provides the background necessary for understanding child abuse, and presents a four-stage theoretical model for therapeutic intervention. Detailed case studies are included.
Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs
Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics. This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.
Molecular Diagnostics of Cancer
Precision medicine, also known as personalized medicine, is an innovative approach to medical treatment and diagnosis that takes into account individual variability in genes, environment, and lifestyle for each person. In the context of cancer, precision medicine aims to tailor medical care to the specific genetic and molecular characteristics of each patient's tumor. This allows for more targeted and effective treatments, minimizing side effects and improving outcomes. The first step in precision medicine, especially in oncology, is represented by an accurate diagnosis, including molecular and genetic data. A comprehensive assessment in molecular pathology includes conventional and more inn...
History of Romanian Technology and Industry
This volume showcases the valuable achievements of the Romanian technology and industry worldwide. It started from the premise that the history of Romanian technique is scarcely known outside the borders of Romania. The main Romanian contributions to the world’s technological heritage are missing, except for a few names in the field of aviation, from the great encyclopedias and dictionaries published worldwide. This is due, among other reasons, to the insufficient promotion in widely spoken languages of the history of Romanian technology. The multidisciplinary approach of the volumes means that the field of technology had to be split into several branches. The present volume includes the f...
The Chemical Biology of Long Noncoding RNAs
This book offers a comprehensive and detailed overview of various aspects of long non-coding RNAs. It discusses their emerging significance in molecular medicine, ranging from human cancers to cardiovascular and metabolic diseases. Transcriptomic studies have demonstrated that the majority of genomes found in complex organisms are expressed in highly dynamic and cell-specific patterns, producing huge numbers of intergenic, antisense and intronic long non-protein-coding RNAs (lncRNAs). Thousands of lncRNAs have been identified, and unlike mRNA, they have no protein-coding capacity. A large repertoire of ncRNAs, actively transcribed from the mammalian genome, control diverse cellular processes...
The Logic of Social Practices
This book reports on cutting-edge research concerning social practices. Merging perspectives from various disciplines, including philosophy, biology, and cognitive science, it discusses theoretical aspects of social behavior along with models to investigate them, and also presents key case studies. Further, It describes concepts related to habits, routines, and rituals and examines important features of human action, such as intentionality and choice, exploring the influence of specific social practices in different situations. Based on a workshop held in June 2018 at the 6th World Congress of Universal Logic, UNILOG2018, in Vichy, and including additional invited chapters, the book offers fresh insights into the fields of social practice and the cognitive, computational, and philosophical tools to understand them.
The New Pioneer
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