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An Introduction to Genetic Epidemiology
This book brings together leading experts to provide an introduction to genetic epidemiology that begins with a primer in human molecular genetics through all the standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field.
Systematic Reviews in Health Care
The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
Combining Human Genetics and Causal Inference to Understand Human Disease and Development
Mendelian randomization and related techniques allow researchers to use knowledge about genetic factors that contribute to a disease to predict whether other risk factors, such as environmental exposure, play a part. This volume examines how these approaches allow researchers to make causal inferences about modifiable exposures and how this can benefit public health. Topics covered in this essential volume include: - The Meaning of "Cause" in Genetics - Twins and Causal Inference: Leveraging Nature's Experiment - Mendelian Randomization: Concepts and Scope - Integrating Family-Based and Mendelian Randomization Designs - Computational Tools for Causal Inference in Genetics - Using Mendelian Randomization to Improve the Design of Randomized Trials
Health Inequalities
The lifecourse perspective on adult health and on health inequalities in particular, is one of the most important recent developments in epidemiology and public health. This book brings together, in a single volume, the work of one of the most distinguished academics in the field. It is the first to specifically take a lifecourse approach to health inequalities and will be essential reading for academics, students and policy makers with an interest in public health, epidemiology, health promotion and social policy.
The Grim Reaper's road map
This impressive full-colour atlas, with over 100 colour-coded and accessible maps, uniquely presents the geography of death in Britain. The first atlas published on this subject for over two decades, this book presents data from more than 14 million deaths over a 24-year period in Britain. The maps detail over 100 separate categories of cause of death, including various cancers, suicides, assault by firearms, multiple sclerosis, pneumonia, hypothermia, falls, and Parkinson's disease, and show how often these occurred in different neighbourhoods. Accompanying each map is a detailed description and brief geographical analysis - the number of people who have died due to each cause, the average age of death and ratio of male to female deaths are listed. Taken as a whole, these provide a comprehensive overview of the geographical pattern of mortality in Britain. This atlas will be essential reading for academics and students of social medicine, sociology of health and illness and epidemiology. It will also be valuable for anyone who wants a better understanding of patterns of mortality within Britain, including medical and healthcare practitioners, policy makers and researchers.
The Sociology of Health Inequalities
Leading researchers in the social sciences describe and explain the unequal chances of long and healthy life between social groups, ethnic groups, men and women and geographical areas.
Epigenetic Epidemiology
The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored.This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laborator...
Systematic Reviews in Health Research
Systematic Reviews in Health Research Explore the cutting-edge of systematic reviews in healthcare In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including: Twelve new chapters, covering additi...
The widening gap
Relentlessly, the wide health gap between different groups of people living in Britain continues to get even wider. This book presents new evidence (which was not available to the government's Independent Inquiry into Inequalities in Health) on the size of the gap, and the extent to which the gap is widening. In particular, new geographical data are presented and displayed in striking graphical form. It challenges whether the government is concerned enough about reducing inequalities and highlights the living conditions of the million people living in the least healthy areas in Britain. It presents explanations for the widening health gap, and addresses the implications of this major social ...
Uses of Epidemiology
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