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It is widely recognized that the degree of development of a science is given by the transition from a mainly descriptive stage to a more quantitative stage. In this transition, qualitative interpretations (conceptual models) are complemented with quantification (numerical models, both, deterministic and stochastic). This has been the main task of mathematical geoscientists during the last forty years - to establish new frontiers and new challenges in the study and understanding of the natural world. Mathematics of Planet Earth comprises the proceedings of the International Association for Mathematical Geosciences Conference (IAMG2013), held in Madrid from September 2-6, 2013. The Conference addresses researchers, professionals and students. The proceedings contain more than 150 original contributions and give a multidisciplinary vision of mathematical geosciences.
This detailed volume explores the use of single-cell assays in research for drug discovery, microfluidics, and more. The book delves into methodologies involving a variety of cell types and diseases, small molecules and biologics, as well as studies of the genome and transciptome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Single-Cell Assays: Microfluidics, Genomics, and Drug Discovery serves to enable researchers to obtain a rapid overview in state-of-the-art microfluidic single-cell assays and an impression of what possibilities these assays offer to drug discovery.
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