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Growth hormone (GH) or somatotropin (STH) is a protein hormone that stimulates growth and cell reproduction in humans and other animals. It is a 191-amino acid; single chain polypeptide hormone which is synthesised, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland. HGH promotes growth in children and plays an important role in adult metabolism. The body secretes the hormone, in decreasing amounts, throughout our lifetimes. The amount of hormone in the body can be measured by levels of IGF-1 (Insulin Growth Factor). Growth hormone has a profound effect on all the cells of the body, more than any other hormone because it is the cell generator. This book presents the latest research in the field.
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“This valuable and penetrating little book deals with one of the baffling problems of our age, namely the relation between Nazi and German... The thesis of the book is that the traditional German character is derived from a rigid, authoritarian, static family system which adapted itself readily to the Nazi pattern and remained essentially unaltered when the Nazi layer was stripped away. The implication is that German and Nazi are more nearly identical than is realized by naïve exponents of ‘denazification’... a well-written, sensible book suggestive as to methodology and rich in wisdom...” — The Annals of the American Academy of Political and Social Science “An interesting study...
In a state-of-the-art synthesis of basic science and clinical practice, Roy Smith and a distinguished panel of researchers and clinicians review GH regulation and its action at the molecular level, and describe the basis for GH deficiency and the use of GH as therapy in a variety of clinical situations. The clinical presentation moves beyond the treatment of GH-deficient children to include the genetics of GH-deficiency, GH-deficiency in adults, osteoporosis, Syndrome X, sleep quality, GH in AIDS patients, GHRH in clinical studies. Timely and innovative, Human Growth Hormone: Research and Clinical Practice will benefit both basic and clinical researchers, as well as those clinical endocrinologists who want to use growth hormone not only in treating children, but also in treating adult disorders, including those associated with metabolic disease.
Over the past years, great advances have been made in the research of Prader-Willi Syndrome and its treatment options. The results raise hopes that the once depressing outlook for children with PWS and their parents will gradually give way to a much improved quality of life. Clinical research has shown that there is a hypothalamic growth hormone deficiency in PWS and that growth hormone treatment improves body composition, body proportions and physical performance of patients. Increased lean body mass enhances energy expenditure and - provided the energy input can be restrained - children no longer become obese. The disappearance of the obese phenotype in children with PWS who are treated wi...
'A persuasive and beautifully written take on how languages are constantly evolving... an enthralling read about human psychology and anthropology as well as linguistics.' ALEX BELLOS ___________________________________ 'Language is mankind's greatest invention - except of course, that it was never invented'. So begins Guy Deutscher's fascinating investigation into the evolution of language. No one believes that the Roman Senate sat down one day to design the complex system that is Latin grammar, and few believe, these days, in the literal truth of the story of the Tower of Babel. But then how did there come to be so many languages, and of such elaborate design? If we started off with rudime...
It is the call Scotland Yard Superintendent Duncan Kincaid never expected -- and one he certainly doesn't want. Victoria, his ex-wife, who walked out without an explanation more than a decade ago, asks him to look into the suicide of local poet, Lydia Brooke -- a case that's been officially closed for five years. The troubled young writer's death, Victoria claims, might well have been murder. No one is more surprised than Kincaid himself when he agrees to investigate -- not even his partner and lover, Sergeant Gemma James. But it's a second death that raises the stakes and plunges Kincaid and James into a labyrinth of dark lies and lethal secrets that stretches all the way back through the twentieth century -- a death that most assuredly is murder, one that has altered Duncan Kincaid's world forever.
In the tradition of P. D. James, Elizabeth George, and Louise Penny, New York Times bestselling author Deborah Crombie spins an engrossing, emotionally powerful tale of conspiracy, betrayal, and double-dealings that will bring home the chilling consequences of murder to Scotland Yard detectives Duncan Kincaid and Gemma James. Recently uprooted and feeling his way in his new posting to Camden—an eclectic area of London's counterculture, as well as it's greatest travel hub—Superintendent Kincaid is plunged into the investigation of a fatal bombing during a protest at St. Pancras Station. The already sensitive enquiry is almost immediately complicated by a set of strange circumstances and c...