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Extensively updated and expanded, this second edition of a bestseller distills the current state-of-the-science and provides the nuts and bolts foundation of the methods involved in this rapidly growing science. With contributions from pioneering researchers, it includes microwire array design for chronic neural recordings, new surgical techniques for chronic implantation, microelectrode microstimulation of brain tissue, multielectrode recordings in the somatosensory system and during learning, as well as recordings from the central gustatory-reward pathways. It explores the use of Brain-Machine Interface to restore neurological function and proposes conceptual and technical approaches to human neural ensemble recordings in the future.
An estimated 40 million Americans and millions of others worldwide suffer from some type of sleep disruption or disorder, and these numbers are rapidly increasing. As biomedical technologies advance our understanding of sleep, a wave of developments in sleep research and the emergence of new technologies offer hope and help for a good night‘s
La neurochirurgie stéréotaxique chez le rongeur de laboratoire représente une discipline contemporaine fondamentale permettant d’aborder de manière précise et ponctuelle le fonctionnement du système nerveux central ainsi que ses dysfonctionnements. Ses techniques sont couramment utilisées dans les laboratoires de recherche par des expérimentateurs issus de parcours très différents. Après une introduction rappelant les bases de la neuro-anatomie descriptive et fonctionnelle chez le rongeur, ce Précis de neurochirurgie stéréotaxique appliquée aux rongeurs de laboratoire guide pas à pas l’expérimentateur depuis la description des atlas de stéréotaxie à la prise de coordo...
?뇌와 기계가 만날 때, 누구도 상상하지 못한 새로운 세상이 펼쳐진다! 인류의 미래를 송두리째 바꿔놓은 최첨단 뇌과학의 모든 것 뇌-기계 인터페이스(BMI, brain-machine interface)라고 이름붙인 혁명적인 신경생리학 패러다임에 관한 연구와 예상 시나리오를 담은 책이다. BMI를 이용해 뇌를 신체의 한계에서 해방시키고, 가상의 전기적ㆍ기계적 도구를 이용해서 오로지 생각만으로 물리 세계를 조정하는 세상이 가능해진다. 이 책은 그 실험들과 그것을 통해 뇌의 기능을 어떻게 다르게 이해하게 되었는지에 대한 이야기들이 실려있...
This book focuses on the neuropsychopharmacology of serotonin and its role in sleep and wakefulness, presenting neurochemical, electrophysiological, and neuropharmacological approaches to understand the mechanisms of serotonin and related substances. Covering core and contemporary topics in the area, this volume is valuable for all researchers interested in interdisciplinary studies concerning drugs affecting the central nervous system.
Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology.
Spanning over half a century of investigation into Rapid Eye Movement (REM) sleep, this volume provides comprehensive coverage of a broad range of topics in REM sleep biology. World renowned researchers and experts are brought together to discuss past and current research and to set the foundation for future developments. Key topics are covered in six sections from fundamental topics (historical context and general biology) to cutting-edge research on neuronal regulation, neuroanatomy and neurochemistry, functional significance and disturbance in the REM sleep generating mechanism. A reference source for all aspects of REM sleep research, it also incorporates chapters on neural modelling, findings from non-human species and interactions between brain regions. This is an invaluable resource, essential reading for all involved in sleep research and clinical practice.
Handbook of Behavioral State Control: Cellular and Molecular Mechanisms provides the first synthesis of information on the neurobiology of behavioral states, ranging from normal stress and sleep deprivation to debilitating neuropsychiatric disorders. This book presents a working reference on the cellular and molecular mechanisms generating arousal states; pharmacological and non-pharmacological methods of behavioral state control; and the bi-directional interaction between arousal state and the neurobiology of pain, and between sleep and the immune system.
This reference also includes nine color plates. Written by leading international scientists in the field, this comprehensive and up-to-date reference provides detailed coverage of various aspects of rapid eye movement sleep (REMS)-including phylogeny and evolution, ontogeny, neurophysiological and neurochemical phenomena, molecular processes, behavioral and physiological changes due to deprivation, and hypotheses on the neurodynamics of REMS. Examining the relationship between the neocortex in mammals and birds in the evolution of REM sleep, Rapid Eye Movement Sleep considers the roles of REMS in the maturation of the brain reveals a new theory that challenges the assumption that REM is sole...
L’ipnosi è un fenomeno noto alla comunità medica e psicologica da oltre duecento anni, eppure la sua natura rimane sfuggente. Significative domande su tale esperienza non hanno ancora ricevuto risposte soddisfacenti. Che cos’è l’ipnosi? Come mai una buona parte degli esseri umani ne è suscettibile? Quali sono i principali processi psicologici coinvolti? Franco Fabbro prova a rispondere a questi interrogativi affrontando alcuni grandi temi collegati al fenomeno ipnotico, come la natura eminentemente sociale del cervello degli ominidi, le caratteristiche cognitive degli esseri umani e l’organizzazione degli stati dinamici interni al cervello. Sulla scia degli studi svolti da Gustav...