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Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing
Adverse immune reactions to biomaterials are important bottlenecks for translation of novel biomaterials for clinical use. Moreover, recent advances in highthrough-put biomaterial discovery and synthetic biology, while providing exciting new veues, also significantly increases potential risks related to the in vivo reactions to these new materials. For example, the novel materials might have unintended biological activities due to their natural building blocks. In this perspective, biomaterial field needs i) better understanding of cell/biomaterial interactions at systems level; ii) development of new analysis and testing tools for advanced risk assessment iii) tools and technologies for modulating reactions to biomaterials and iv) advanced in vitro models for understanding and testing of reactions to biomaterials. In the following collection of articles you will find examples of such systems,together with comprehensive reviews of current developments in in vitro model systems. The collection also contains articles that elucidate the immune reaction to biomaterials in vitro and in vitro.
Encounters with the Hidden Imam in Early and Pre-Modern Twelver Shīʿī Islam
In Encounters with the Hidden Imam in Early and Pre-Modern Twelver Shīʿī Islam, Omid Ghaemmaghami traces the history of one of the core ideas that animate and form the highly influential and instrumental belief in the Hidden Imam, the central figure of Twelver Shīʿī messianic expectation.
Handbook of Biomimetics and Bioinspiration
self-assembly and responsiveness of cellular systems; the biomineral formation in bacteria, plants, invertebrates, and vertebrates; the multi-layer structure of skin; the organization of tissue fibers; DNA structures with metal-mediated artificial base pairs; and the anisotropic microstructure of jellyfish mesogloea. In this volume, sensor and microfluidic technologies combined with surface patterning are explored for the diagnosis and monitoring of diseases. The high throughput combinatorial testing of biomaterials in regenerative medicine is also covered. The second volume presents nature-oriented studies and developments in the field of electromechanical devices and systems.
Handbook Of Biomimetics And Bioinspiration: Biologically-driven Engineering Of Materials, Processes, Devices, And Systems (In 3 Volumes)
Global warming, pollution, food and water shortage, cyberspace insecurity, over-population, land erosion, and an overburdened health care system are major issues facing the human race and our planet. These challenges have presented a mandate to develop “natural” or “green” technologies using nature and the living system as a guide to rationally design processes, devices, and systems. This approach has given rise to a new paradigm, one in which innovation goes hand-in-hand with less waste, less pollution, and less invasiveness to life on earth. Bioinspiration has also led to the development of technologies that mimic the hierarchical complexity of biological systems, leading to novel ...
Handbook of Biomimetics and Bioinspiration
Global warming, pollution, food shortage, security, and health care are major issues facing us and our planet. These global challenges have inspired scientists and engineers to design materials, processes, and enabling tools that mimic nature and are less intrusive. The aim of the Handbook of Biomimetics and Bioinspiration is to serve as a reference on synthesis, modification, assembly, packaging, transportation, targeting, and recognition at their destination, conservation of information and response to foreign invadors, the creation of a dynamic living system from these assemblies, and the use of the principles governing biological systems for creating novel biomimetic systems. Presented in a set of three volumes, this handbook covers biomimetics and bioinspiration within the scope of materials, mechanics, dynamics, transport, chemical reactions, control, recognition, and informatics.
Computational Bioengineering and Bioinformatics
This book explores the latest and most relevant topics in the field of computational bioengineering and bioinformatics, with a particular focus on patient-specific, disease-progression modeling. It covers computational methods for cardiovascular disease prediction, with an emphasis on biomechanics, biomedical decision support systems, data mining, personalized diagnostics, bio-signal processing, protein structure prediction, biomedical image processing, analysis and visualization, and high-performance computing. It also discusses state-of-the-art tools for disease characterization, and recent advances in areas such as biomechanics, cardiovascular engineering, patient-specific modeling, population-based modeling, multiscale modeling, image processing, data mining, biomedical decision-support systems, signal processing, biomaterials and dental biomechanics, tissue and cell engineering, computational chemistry and high-performance computing. As such, it is a valuable resource for researchers, medical and bioengineering students, and medical device and software experts
