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This new, revised and updated edition takes into account the most recent advances in the understanding of human pathophysiology. The book presents the complex basic principles of vascular hemodynamics and its pathophysiologie in a direct and effective way, stressing the importance of the mechanical properties of large arteries in the origin of blood pressure. The readily understandable text, supported by helpful images, describes the elements that define blood pressure and explains such important concepts as pulse wave velocity, central blood pressure, reflected waves, and pulse pressure amplification. Entirely new chapters are included on the sympathetic nervous system and arterial stiffness and on the role played by arterial stiffness in influencing blood pressure variability. The book will enable the physician to answer some of the key questions encountered when addressing the problem of arterial hypertension in everyday clinical practice: How is blood pressure generated? How should blood pressure values be interpreted? Is systolic blood pressure of greater importance than diastolic blood pressure?
This practical volume highlights traditional, novel, and evolving aspects of the diagnosis and treatment of pulmonary embolism (PE). The contributors comprise an international team of experts. Important aspects of diagnosis, risk stratification, and differential treatment of patients with PE are presented in a concise, yet comprehensive manner. Emphasis is placed on specific issues related to PE, including pregnancy, cancer, thrombophilia, and air travel.
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The imposition of strict liability in tort law is controversial, and its theoretical foundations are the object of vigorous debate. Why do or should we impose strict liability on employers for the torts committed by their employees, or on a person for the harm caused by their children, animals, activities, or things? In responding to this type of questions, legal actors rely on a wide variety of justifications. Justifying Strict Liability explores, in a comparative perspective, the most significant arguments that are put forward to justify the imposition of strict liability in four legal systems, two common law, England and the United States, and two civil law, France and Italy. These justif...