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Pharmacological Interventions for Osteoporosis
This book provides readers a fundamental insight into the basic properties of the pharmaceutical agents used in the treatment of osteoporosis. It provides insight into mechanisms of action, updated information on clinical utility, and possible side effects associated with the use of these pharmaceutical agents. In particular, it highlights the use of two monoclonal antibodies romosozumab and denosumab in activating osteoblast differentiation and inhibiting osteoclasts. It also discusses two anabolic pharmaceutical agents, teriparatide and abaloparatide to treat osteoporosis. They have been shown to reduce the incidence of non-vertebral and vertebral fractures significantly after they were administered to patients daily as subcutaneous injections. The content of this book caters to researchers, scientists, and clinical practitioners who are interested in the treatment of osteoporosis using pharmaceutical agents.
Innovative Bioceramics in Translational Medicine II
This book is part of a two-part volume book that highlights the latest advances in innovative bioceramics applied in the highly interdisciplinary area referred to as “translational medicine”. This volume predominantly written by surgeons in the fields of craniomaxillofacial, orthopedics, and spinal surgery, examines the translation of innovative bioceramics and bioceramics-based composite from the laboratory to a personalized surgical environment for the repair of damaged and diseased bone tissues. This book also covers the topic of osteoporosis, a skeletal disorder in which the World Health Organization (WHO) has recognized it as a public health emergency due to the high number of subjects who exhibited the disease and the morbidity and mortality related to fractures. The book caters to biomaterials researchers and medical clinicians who are interested in incorporating innovative bioceramics to the above-mentioned applications.
The Role of the Muscle Secretome in Health and Disease
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Imaging of Prosthetic Joints
An increasing percentage of the population has at least one prosthetic joint. Imaging is required for both initial assessment and routine follow-up of the implant, and this book is intended as an informative and up-to-date guide to the subject. After an introductory section covering a range of background topics, the level of information offered by different imaging techniques in presurgical planning and postimplantation assessment is analyzed. The application of imaging to different joints is then carefully explored in chapters devoted to the foot and ankle, hip, knee, shoulder, and elbow, wrist and hand. In addition, two innovative chapters focus on periprosthetic DXA as the gold standard in monitoring implant survival and on the role of drug therapy in helping to ensure the durability of the prosthesis. A central feature of the book is its combination of the clinical and radiological perspectives; it will be of value to radiologists and orthopedic specialists, as well as residents in these disciplines.
