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Cancer is one of the major health problems of our time and liver cancer is responsible for over one million deaths per year world-wide, making it the fourth most common cause of death from cancer. Surgical resection of the tumour(s) is the treatment of choice and offers the only chance of prolonged survival. Yet the best attempts are often frustrated by either advanced or co-existent disease that renders the patient non-resectable. This book tackles the many options available to doctors and patients in an attempt to combat this desperate disease.
Induction chemotherapy, as part of an integrated plan of management for locally advanced cancers, is being practiced throughout the world, but frequently teams are unaware of the work being undertaken in other institutions. This book aims to present the full range of management techniques used in induction chemotherapy within one accessible volume. It provides up-to-date information on pioneering and cutting edge practices and documents the advantages of integrated treatment schedules. Patient selection is discussed, and each of the cancer types for which induction therapy has proved important is considered in detail. All who are responsible for the treatment of patients with locally advanced cancers will find this book to be an invaluable source of information. It will be particularly interesting for specialist oncologists aiming to set up fully comprehensive cancer centers and for health administrators wishing to learn about the benefits of establishing such centers in strategic locations.
Despite lifestyle improvements, the incidence of rectal cancer is increasing in industrialised countries. Rapid advances in technology, growing knowledge of the biological history of the disease and closer attention to patients' quality of life after surgery have led to a less invasive approach. In the last 15 years, the surgical approach has shifted from extended resection to sphincter-saving procedures, featuring a multidisciplinary approach and a high level of specialisation. The experienced surgeon can plan and choose the "right treatment for the right patient" only with the support of the radiologist, endoscopist and pathologist (preoperative staging), oncologist and radiotherapist (neo...
Malignant effusions (pleurites, ascites and pericarditis) are some of the most frequent manifestations of dissemination process of malignant tumors. Accumulation of the malignant fluid in serous cavities results in impairment of respiratory and cardiac functions, however long-term evacuation of the fluid leads to severe disorders of homeostasis that may directly cause the patient’s death. The aim of this comprehensive book is to provide detailed information of pathogenesis and management of malignant effusions. The current book focuses on three of these categories: pleuritis, acsites and pericarditis. This book, written by recognized experts in the field, provides a detailed overview of cu...
This volume provides a biological and pharmacological background for regional cancer therapy, strategies and techniques for regional therapies, and specific indications and results for different tumor entities. Clinical trial concepts and detailed treatment protocols are also presented. This book is essential reading for researchers and clinicians engaged in seeking advanced therapeutic options for cancer patients worldwide.
Totally updated and revised to include a synopsis of the current wealth of literature available, this bestselling text still retains its original purpose which is to provide an indispensable compendium of all the current information and studies on breast cancer.
Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies.
This book is a printed edition of the Special Issue "Chemical and Molecular Approach to Tumor Metastases" that was published in IJMS
Adrenal tumors are commonly encountered in the practice of radiology (adrenal incidentalomas). They may arise from the adrenal gland itself, either the cortex or the medulla, or they could be secondary lesions, and they may be benign or malignant. When an adrenal tumor is identified, the key clinical questions are whether it is functioning and whether it is malignant. It is vital to be familiar with imaging characteristics of adrenal tumors for appropriate diagnosis and management. Regarding functionality, although 75% of adrenal tumors are non-functioning cortical adenomas, there is a subset of these masses with important clinical consequences (i.e. primary adrenal cancer or metastases to adrenal glands, pheochromocytoma and functional tumors that secrete cortisol, aldosterone or androgens). The delayed or false diagnosis may lead to development of severe complications of excess of secreted hormones (e.g. resistant hypertension, diabetes mellitus, osteoporosis in case of hypercortisolaemia, hypertensive crisis or myocardial infarction in case of pheochromocytoma) or metastases (in case of primary adrenal cancer of malignant pheochromocytoma).