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Umbrella Reviews
This book is an ideal guide to umbrella reviews, overviews of reviews, and meta-epidemiologic studies for evidence synthesis. Research is conducted at different levels: primary research consists of original studies while secondary research comprises qualitative reviews, systematic reviews, and meta-analyses. Recently, a novel further level of research has been introduced, based on the analysis and pooling of reviews and meta-analysis. This book is the first to focus solely on this new type of research design, which permits a comprehensive and powerful synthesis of scientific evidence in medicine as well as in many other fields in order to inform decision-making. All aspects are covered, including review design and registration, the searching, abstracting, appraisal, and synthesis of evidence, the appraisal of moderators and confounders, and state of the art reporting. Case studies in a range of medical specialties are then presented. The hands-on approach of the book, written by a multinational team of experts, will enable the reader to interpret and independently conduct umbrella reviews.
Diagnostic Meta-Analysis
This book is the first exclusively devoted to the systematic synthesis of diagnostic test accuracy studies. It builds upon the major recent developments in reporting standards, search methods, and, in particular, statistical tools specifically devoted to diagnostic studies. In addition, it borrows extensively from the latest advances in systematic reviews and meta-analyses of intervention studies. After a section dedicated to methods for designing reviews, synthesizing evidence and appraising inconsistency in research, the application of these approaches is demonstrated in the context of case studies from various clinical disciplines. Diagnosis is central in medical decision-making, and in m...
Hybrid Cardiac Imaging for Clinical Decision-Making
Performing any diagnostic test in medicine is always a matter of trying to get the condition of the patient diagnosed properly with the least effort, exposure, discomfort and at the same time with the lowest possible error probability. Pre-test probability is helpful but often imprecise, effectively overestimating the patient's risk profile. In a broader prevention objective, the phases of a disease, its onset, progression, and complications must be taken into account. The negative predictive value, which is so important, has in turn its main limitation in identifying the healthy patient, that is, the one who does not belong to any cluster of patients in which we would act in terms of preven...
Transcatheter Aortic Valve Implantation
This book provides comprehensive information on transcatheter aortic valve implantation (TAVI), which was introduced for the treatment of aortic valve disease less than two decades ago. It explains how TAVI has delivered satisfactory results even in high and intermediate risk patients and outlines how it continues to evolve, thus requiring awareness of state of the art approaches to indication, risk stratification, device choice, procedure, and follow-up. In addition, it reports on the complex and multidisciplinary approach needed to maximize the efficacy, safety, and appropriateness of TAVI, providing detailed clinical, interventional and surgical perspectives focusing on the development of this cardiovascular intervention. Starting with the history of TAVI, addressing the interventional anatomy of aortic valve disease, and reporting on the expert authors’ day-to-day experiences, this highly informative book offers an essential update for all cardiologists and surgeons interested in transcatheter aortic valve implantation, as well as any clinician, decision-maker and stakeholder involved in patient selection, procedural management, and follow-up.
Contrast Media
Two years only after the publication of the ? rst edition of “Contrast media – Safety issues and ESUR guidelines” in our book series Medical Radiology in 2006, it appeared that a second edition was urgently needed. The ? rst edition was indeed an exceptional success with our readership and sold out rapidly, but moreover the safety of MR contrast media urgently required a reappraisal after the publication of a new and dramatic adverse reaction to some of the gadolini- based agents: the so called NSF syndrome. I am very much indebted to Professor Henrik S. Thomsen and his academic colleagues from the ESUR Contrast Medium Safety Committee for accepting the task to prepare a second edition...
Psychotherapy for Ischemic Heart Disease
This book discusses the benefits of application of different psychotherapy techniques, in addition to optimal medical approaches, in patients with ischemic heart disease. It explains the theoretical basis for use of these techniques, discusses the scientific evidence for their efficacy, and identifies important practical issues. Detailed attention is devoted to both well-established and recently developed approaches of proven value, as well as to future applications. In addition, practical insights are provided into the most effective ways of integrating psychotherapy with medical activities in hospitals, outpatient clinics, and rehabilitation centers. The authors are world experts in the fields of psychotherapy, pharmacology, and cardiology, who collectively provide a sound foundation for an interdisciplinary approach to patients with ischemic heart disease. Psychotherapy for Ischemic Heart Disease is both a textbook and a practical manual aimed particularly at cardiologists, psychologists, psychotherapists, and psychiatrists, but also internal medicine specialists, cardiac surgeons, general practitioners, rehabilitation doctors, students, nurses, and patients.
Renal denervation
This Renal Denervation handbook is a practical “all you need to know” guide to treating patients with hypertension. Renal Denervation is a revolutionary, minimally invasive trans-catheter intervention that has emerged as a safe and effective therapeutic companion for the limited number of patients with resistant hypertension and the huge population of those who “resist” to take their prescribed medications. Written by the world’s most recognized experts in the field, the handbook provides a review of the scientific bases of the therapy, reveals practical instructions on how to select the right patients and perform the procedure, and analyzes clinical results in a direct, easy to understand style. This guide is the resource for all healthcare providers interested in the modern management of hypertension and successfully managing the number one risk factor for stroke, myocardial infarction, and heart failure worldwide.
New Research on Aspirin and Health
In 1763, Reverend Edmund Stone took the first step toward the discovery of one of the most commonly used medicines when he noted that the bark of the English willow was an effective treatment for patients suffering from a fever. This synthesised compound would eventually become known as one of the most prescribed drugs for acute and chronic pain symptoms. However, through years of trial and error, this drug has been the subject of many controversial issues. Aspirin serves as one of the leading agents for cardiovascular treatment in women. However, many patients have experienced negative side effects of internal bleeding and lining damage due to strong amounts of acid in the drug. Aspirin is often effective when taken in small doses. This book brings together medical and biological research. These involve neurological effects, clinical and experimental reactions, lung exposure, withdrawal symptoms, cardiovascular side effects, uses in cancer treatment and many other application areas.
The “Cardiology case” - My life. My truth
The protagonist of the “Cardiology Case” of Modena tells her own story. At the time, 2013, of publication of this book in Italy, than two years since the beginning of the story, she was still waiting to be judged, and after being “trampled morally and professionally”, she decided to let know “her” truth publishing documents, e- mails, minutes, reports, newspaper articles, etc. concerning the “Case”.
