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In the last two decades, due to the continuous increase of lifespans in Western societies, and the consequent growing of the elderly population, have witnessed an increase in the number of studies on biological and molecular factors able to promote healthy aging and reach longevity. The study of the genetic component of human longevity demonstrated that it accounts for 25% of intra population phenotype variance. The efforts made to characterize the genetic determinants suggested that the maintenance of cellular integrity, inflammation, oxidative stress response, DNA repair, as well as the use of nutrients, represent the most important pathways correlated with a longer lifespan. However, alth...
"Originally published in 2010 in Australia by HarperCollinsPublishers Australia Pty Limited"--Title page verso.
Includes entries for maps and atlases.
Dos hermanas huérfanas que viven en un pequeño pueblo de Italia emigran a América a principios del siglo XX. Llegan a Nueva York y se instalan en Little Italy, el barrio italiano de la Gran Manzana, donde encuentran trabajo en una fábrica de textiles. Arman allí una nueva vida, compartida con otras mujeres inmigrantes, hasta que un incendio fatal en la fábrica cambiará drásticamente su destino. Dos hermanas huérfanas, que viven en un pequeño poblado en Italia, deciden emigrar a América siguiendo los deseos de su madre. Estamos en los primeros años del siglo XX, cuando la emigración europea al continente americano estaba en pleno apogeo. El plan inicial era viajar a la Argentina,...
In these three exotic, steamy dramas Tennessee Williams portrays loss, faded lives and passionate love affairs. The Rose Tattoo is set in a bustling, Sicilian-American community, where newly widowed Serafina is paralysed by grief, until she has her romantic illusions about her dead husband shattered and rediscovers her true nature as a fiery prima donna, in a life-affirming celebration of love and sex. Tennessee Williams explores a new 'wild and unrestricted' theatrical form in the colourful tropical fantasy Camino Real, while Orpheus Descending, however, takes us into the dark territory of the Deep South: the corrupt hell of a small, brutal township, where a forbidden and tragic love affair sparks horrific violence.
This state-of-the-art review on longevity focuses on centenarians, studied as a model of positive biology. The extraordinary rise in the elderly population in developed countries underscores the importance of studies on ageing and longevity in order to decrease the medical, economic and social problems associated with the increased number of non-autonomous individuals affected by invalidating pathologies. Centenarians have reached the extreme limits of human life span. Those in relatively good health, who are able to perform their routine daily tasks, are the best examples of extreme longevity, representing selected individuals in which the appearance of major age-related diseases – includ...
Profiles the works of Tennessee Williams and provides information on his life and writing career.