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The Past and the Future of Human Immunity Under Viral Evolutionary Pressure
There is a long-standing evolutionary battle between viruses and their hosts that continues to be waged. The evidence of this conflict can be found on both sides, with the human immune system being responsive to new viral challenges and viruses having developed often sophisticated countermeasures. The “arms race” between viruses and hosts can be thought as an example of the “Red Queen” race, an evolutionary hypothesis inspired from the dialogue of Alice with the Red Queen in Lewis Carroll’s “Through the Looking-Glass”. At the same time, viruses have a minimal genomic content as they have evolved to hitchhike biological machinery of their hosts (or other co-infecting viruses). T...
Hepatitis C: Epidemiology, Prevention and Elimination
This volume focuses on epidemiology, genetic diversity and global distribution of Hepatitis C, as well as laboratory diagnosis. Furthermore, the book explores the natural history of the virus and discusses international elimination strategies. The two volume work on Hepatitis C introduces to the topic by reviewing virology, diagnosis, epidemiology, prevention and elimination of HCV. The book provides a valuable source at full length for researchers and clinicians working on Hepatitis C.
Virus Infected Cells
Virus-infected Cells is a comprehensive and technical exploration of the intricate interactions between viruses and host cells. This book delves into the molecular and cellular aspects of viral infections, providing a wealth of knowledge about various viruses and their effects on cellular mechanisms. The first part of the book covers general/technical aspects, introducing the reader to the field of virology and providing an overview of the techniques used to study virus-infected cells. It covers topics such as the visualisation of virus-infected cells by cryo-electron tomography and the assessment of necroptosis, a type of programmed cell death, in virus-infected cells. In addition, the book...
Endogenous Viral Elements – Links Between Autoimmunity and Cancer?
In this eBook, original and review papers on various aspects of endogenous viral elements (EVEs) are included. EVEs are integral parts of the genomes of eukaryotic organisms and are involved in various physiological and pathological processes. The focus of this eBook is on the involvement of EVEs in cancer and autoimmune diseases. Frontiers in Microbiology 3 February 2019 | EVEs, Autoimmunity and Cancer In particular, research on endogenous retroviruses and endogenous bornaviruses is included. The presented data demonstrate that EVEs are fascinating objects that are still worth exploring.
Drug and Therapy Development for Triple Negative Breast Cancer
Drug and Therapy Development for Triple Negative Breast Cancer The first comprehensive and up-to-date compilation of modern diagnostic and treatment methods for triple negative breast cancer In Drug and Therapy Development for Triple Negative Breast Cancer, a team of distinguished practitioners delivers an in-depth and authoritative discussion of contemporary methods for treating triple negative breast cancer (TNBC). The editors have included material that covers its molecular causes, initial detection, diagnostic tools, treatment procedures, pharmacology, and new and experimental therapies—including nanotherapeutics and photothermal therapies. As the first comprehensive compilation of mod...
Recent Progress in Understanding the Mechanism and Consequences of Retrotransposon Movement
This book is a printed edition of the Special Issue "Recent Progress in Understanding the Mechanism and Consequences of Retrotransposon Movement" that was published in Viruses
An Anthropology of Biomedicine
In this fully revised and updated second edition of An Anthropology of Biomedicine, authors Lock and Nguyen introduce biomedicine from an anthropological perspective, exploring the entanglement of material bodies with history, environment, culture, and politics. Drawing on historical and ethnographic work, the book critiques the assumption made by the biological sciences of a universal human body that can be uniformly standardized. It focuses on the ways in which the application of biomedical technologies brings about radical changes to societies at large based on socioeconomic inequalities and ethical disputes, and develops and integrates the theory that the human body in health and illness...
The Reaper’s Dance
From the suburbs of Washington, D.C. and Northern Virginia to the bat infested caves of Wuhan, China, this book traces the myriad networks of the virus that brought the world to its knees. Ravi R. Iyer, M.D. gives readers a ringside seat to the COVID-19 pandemic, highlighting the calculations of those who influenced the fate of millions and the science that saved the world. The author analyzes the various forces and decisions that unleashed the most catastrophic disaster mankind has experienced in this century while zeroing in on the horror, pain, struggles, and triumphs of common people who faced the coronavirus. Written in a fast-flowing style, the book explores how patients battled the disease and how science may have unleashed it on the world. From the failures of governments and leaders to the triumphs of individual men, The Reaper’s Dance is a story of the tapestry of human hubris and humility, courage, and cowardice with an enduring cautionary message for all mankind.
