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This book describes the strategy used for sequencing, assembling and annotating the tomato genome and presents the main characteristics of this sequence with a special focus on repeated sequences and the ancestral polyploidy events. It also includes the chloroplast and mitochondrial genomes. Tomato (Solanum lycopersicum) is a major crop plant as well as a model for fruit development, and the availability of the genome sequence has completely changed the paradigm of the species’ genetics and genomics. The book describes the numerous genetic and genomic resources available, the identified genes and quantitative trait locus (QTL) identified, as well as the strong synteny across Solanaceae species. Lastly, it discusses the consequences of the availability of a high-quality genome sequence of the cultivated species for the research community. It is a valuable resource for students and researchers interested in the genetics and genomics of tomato and Solanaceae.
Melatonin: Biosynthesis, Physiological Effects, and Clinical Applications provides a thorough review of recent advances in major areas of melatonin research. The book is arranged in a logical sequence, beginning with the history of melatonin and then proceeding to cover its biochemistry and secretion, physiological effects, and clinical significance. New findings and current concepts are emphasized, and a significant amount of previously unpublished data are included. The book will be an important reference for neurobiologists, cell biologists, ophthalmologists, endocrinologists, neuroendocrinologists, reproductive biologists, psychiatrists, and other researchers and clinicians interested in melatonin.
Part of the authoritative Oxford Textbooks in Psychiatry series, Oxford Textbook of Old Age Psychiatry, Third Edition has been thoroughly updated to reflect the developments in old age psychiatry since publication of the Second Edition in 2013, and remains an essential reference for anyone interested in the mental health care of older people.
As many as 80% of patients will suffer from back pain at some point in their lifetime. It is the most common form of disability, and the second largest cause of work absenteeism. An early, proactive management approach offers the best route to minimizing these conditions. Renowned authority Curtis W. Slipman, MD and a team of multidisciplinary authorities present you with expert guidance on today's best non-surgical management methods, equipping you with the knowledge you need to offer your patients optimal pain relief. Refresh your knowledge of the basic principles that must be understood before patients with spinal pain can be properly treated. Know what to do when first-line tests and the...
Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.
Covering both primary and revision total knee arthroplasty (TKA), each technique-oriented chapter in this book opens with a clinical case and an overview of the challenges and multiple options for management, and each section within the chapter will describe the physical exam, surgical approach, clinical outcome and recent supporting literature. Chapters will utilize bullet points for quick reference and plentiful intra-operative photos to illustrate the various techniques described. Part one covers primary TKA, with cases demonstrating management strategies for the varus and valgus knee, flexion contracture, patellofemoral arthritis, and extra-articular deformity, among others, while part two covers revision TKA, with cases demonstrating acute infection, flexion and global instability, severe tibial and femoral bone loss, and periprosthetic fracture, among others. Written and edited by experts in the field, Complex Cases In Total Knee Arthroplasty: A Collection of Current Techniques will be a useful reference for orthopedic surgeons, residents and fellows as well as sports medicine specialists and anyone involved in surgical care of the knee.
IPCC Fourth Assessment Report on climate change impacts, adaptation and vulnerability for researchers, students, policymakers.
Capturing the growth of the global medical device market in recent years, this practical new guide is essential for all who are responsible for ensuring safety in the use and manufacture of medical devices. It has been extensively updated to reflect significant advances, incorporating combination products and helpful case examples of current real-l
'Sound and solid case studies on vulnerability and adaptation have been woefully lacking in the international discourse on climate change. This set of books begins to bridge the gap.' Achim Steiner, UN Under-Secretary General and Executive Director of United Nations Environment Programme 'Important reading for students and practitioners alike.' Martin Parry, Co-Chair, Working Group II (Impacts, Adaptation and Vulnerability), Intergovernmental Panel on Climate Change (IPCC) 'Fills an important gap in our understanding ... It is policy-relevant and deserves to be widely read.' Richard Klein, Senior Research Fellow, Stockholm Environment Institute (SEI), Sweden The Intergovernmental Panel on Cl...
This book studies the art and science of analyzing, assessing and anticipating environmental change. Among the issues considered are the observational evidence, the changing public perception of the environment, functions of the environment and its use. Coverage also reviews a series of four prominent cases, namely climate change, the emissions of gasoline lead into the atmosphere and water bodies, fisheries policies and the management of marine oil pollution.