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Along with AIDS, antiphospholipid syndrome was the major medical discovery of the late 20th century, so for many it is still deemed a ‘new’ disease. The discovery of ‘sticky blood’ (commonly known as antiphospholipid syndrome or ‘Hughes Syndrome’) came out of years of observation of patients who had developed lupus. Many specialists in the 1970s were interested in the neurological aspects of lupus, and Dr Hughes, among others, spent a number of years studying the mechanisms of brain inflammation. In the mid 1970s, Hughes observed a number of young women with a form of viral paralysis, where interestingly many of them carried an antibody in their blood actually directed against â€...
Since the original description of antibodies to endothelial cells in the early 1970s, and with the advent of sensitive and reproducible techniques for their detection, the scope for investigating the vascular damage of immunological disorders has widened considerably. In this book, leading world scientists have contributed chapters presenting broad coverage of basic science and clinical implications of immunological interactions of antibodies to endothelial cells. The book takes a multidisciplinary approach that will appeal to immunologists, rheumatologists, internists, and others interested in the subject.
The fourth edition of this best-selling book has been thoroughly revised to take into account recent developments in the law in criminal practice and procedure across the region. The only textbook that explores criminal practice and procedure as it relates to the Commonwealth Caribbean, the book clarifies the state law in each of 11 jurisdictions, at the same time making it clear when laws are the same or similar and highlighting where differences among jurisdictions occur. Both statute law and common law are examined in the relevant jurisdictions, which include Trinidad and Tobago, Guyana, Barbados, Jamaica and Grenada amongst others. The impact of statutory changes in the laws are analysed...
In 1983 Graham Hughes described a syndrome in which the blood has a tendency to clot. Hughes syndrome is at the root of diverse conditions such as stroke, leg vein thrombosis and recurrent abortion. Hughes Syndrome addresses the complete range of features produced by this common disorder, which is also known as antiphospholipid syndrome. The condition can affect any organ, and is treated using commonly available drugs including low-dose aspirin and warfarin. This timely book fulfils the need for a cross-disciplinary clinical textbook and contains contributions from the leading international authorities. Hughes Syndrome should be read by anyone who might have a clinical or scientific interest in this condition: rheumatologists, haematologists, obstetricians and neurologists.
A straightforward and stimulating account of this fascinating area of law that covers all the key topics on undergraduate human rights modules. It includes detailed analysis of key cases throughout that puts the law into context and encourages students to engage with contemporary issues and debates.
An array of carefully selected case report and academic article extracts combined with author commentary to provide a thorough and engaging assessment of criminal law provisions.
This book provides a critical assessment of the problem of internet child pornography and its governance through legal and non-legal means, including a comparative assessment of laws in England and Wales, the United States of America and Canada in recognition that governments have a compelling interest to protect children from sexual abuse and exploitation. The internet raises novel and complex challenges to existing regulatory regimes. Efforts towards legal harmonization at the European Union, Council of Europe, and United Nations level are examined in this context and the utility of additional and alternative methods of regulation explored. This book argues that effective implementation, enforcement and harmonization of laws could substantially help to reduce the availability and dissemination of child pornography on the internet. At the same time, panic-led policies must be avoided if the wider problems of child sexual abuse and commercial sexual exploitation are to be meaningfully addressed.