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The Porphyrins, Volume VI: Biochemistry, Part A deals with the biochemistry of porphyrins, their precursors, catabolic derivatives, and related compounds. The book covers the biosynthesis of porphyrins and chlorophylls; the formation and metabolism of bile pigments in animals and plants; as well as the synthesis, characterization, and chemistry of the bile pigments and their derivatives. An account of the historical and clinical aspects of porphyrins and bile pigments is also given. This volume is organized into 12 chapters and begins with an overview of protoporphyrins and their metabolic intermediates, paying particular attention to their synthesis and biosynthesis. The discussion then shi...
Test developers need to provide a clear explication of the language ability constructs that underpin the tests they offer in the public domain; such an explication is essential for supporting claims about the validity - or usefulness - of test scores. This volume describes the theory and practice of Cambridge ESOL's approach to assessing second language writing ability. A comprehensive test validation framework is used to examine the tasks in Cambridge ESOL writing tests from a number of different validity perspectives that reflect the socio-cognitive nature of any assessment event. The authors show how an understanding and analysis of the framework and its components can assist test develop...
Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.
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