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Platelets are tiny blood cells that help the body form clots to stop bleeding. Antiplatelet medications, such as aspirin and clopidogrel, are commonly used to thin the blood which limits clotting and reduces the risk of heart attack. This book is a comprehensive guide to blood platelets for haematologists. Beginning with discussion on platelet structure, morphology, function and physiology, the next chapters cover the role of calcium in platelet activation and calcium modulation by cyclic nucleotides. The following sections explain the pharmacology of antiplatelet drugs, antiplatelet therapies, aspirin resistance, and the association of diabetes mellitus with major platelet dysfunction. The ...
Diabetes is a disease that occurs when the pancreas does not produce enough insulin to control the amount of glucose in the blood. This book is a comprehensive guide to the latest advances in the diagnosis and treatment of diabetes. Divided into six sections, the manual begins with an overview of diagnosis and classification, followed by discussion on epidemiology and aetiopathogenesis. Section four covers comorbidities and complications of diabetes including hyper- and hypoglycaemia, heart failure, foot ulcers, and diabetic retinopathy. The final sections examine recent advances and technologies. The detailed text is further enhanced by clinical photographs, diagrams and tables to assist learning. Key points Comprehensive guide to latest advances in diagnosis and management of diabetes Discusses diagnosis and classification, epidemiology and aetiopathogenesis Covers many different comorbidities and complications Highly illustrated with clinical photographs, diagrams and tables
Cardiometabolic diseases are a group of metabolic dysfunctions mainly characterized by insulin resistance, impaired glucose tolerance, dyslipidemia, hypertension, and central adiposity that are major contributors to increased risk of acute vascular events such as myocardial infarction, heart failure and stroke. Cardiometabolic Diseases: Molecular Basis, Early Detection of Risks, and Management provides detailed information on all aspects of metabolic dysfunctions and associated risks for cardiometabolic diseases, including a thoughtful discussion of cellular and molecular mechanisms involved in the progression of metabolic risks, the approaches for the early detection and robust management o...
This is the first comprehensive work to review blood platelet biochemistry, physiology, pharmacology, and function. It provides up-to-date information on how platelets function, the biochemical mechanisms that modulate their physiology and function, as well as the pharmacology of platelet inhibitory drugs.
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This book sheds light on the causes, effects, and control of microplastic pollution, providing valuable insights into the tools and techniques for analysis, the impact on ecosystems, and the potential risks to human well-being. The editors focus on the urgency of addressing this global environmental challenge through collaborative efforts and sustainable solutions. This reference features 10 edited chapters covering multiple aspects of microplastic pollution. The book introduces the reader to various tools and techniques used to analyze microplastic pollution in both aquatic and terrestrial ecosystems. It then examines the sources, pathways, and levels of microplastic contamination in the en...
This new edition offers state-of-the-art chapters by distinguished experts in the field of Hematology. The contributors have critically examined and analyzed into perspective some of the contemporary advances and developments and rising torrent of valuable literature of various aspects of hematology. The text is unique in providing the depth and breadth of knowledge in hematology and also a stimulus for further discussion and future research. A multidisciplinary approach with thought provoking articles on exciting topical issues related to hematology contributed by several experts drawn from I.
This is the first book to describe the pharmacological interaction of drugs and exercise with organ systems at molecular and cellular levels. It explains the effect of exercise on pharmacokinetics and pharmacodynamics of drugs, and the activation or induction of antioxidant enzymes which may take place via the adenosine receptor or may occur due to gene expression.