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The book summarizes recent advances in the elucidation of the mechanisms involved in senile osteoporosis as well as its potential treatment, bringing an integrated approach from the bench to the clinical practice. A unique aspect of this book is its emphasis on the application of translational research in the field of osteoporosis and falls. The book provides a complete review on the prevention as well as current and future treatments of osteoporosis.
Osteoporosis Research - Animal Models, presents in a very illustrative and practical manner, general methodologies of bone studies in animals, as well as the particular features of the most commonly used animal models in the field. Research in the field of osteoporosis has grown in recent years. This has resulted in significant advances in determining the causes of osteoporosis, assessing risk factors, and creating new treatment methods. The use of animal models provides important knowledge about pathological conditions that can eventually lead to the development of more effective clinical treatment of diseases in both humans and animals. Osteoporosis Research - Animal Models, is an essential tool for researchers in the bone field. This book aids researchers in selecting their appropriate model and highlights the experiments that can be strategically designed to optimize the potential of an animal to develop the cardinal features of osteoporosis in humans. This book addresses the importance of recent findings from animal models and their significance on the pathogenesis of osteoporosis in relation to human disease.
Falls, fractures, frailty, osteoporosis and sarcopenia are highly prevalent in older persons. While the concept of osteosarcopenia is new, it is a rapidly evolving and cross-disciplinary problem. Prevention and treatment are challenging and a combined therapeutic approach is needed. Osteosarcopenia provides evidence-based information on how to prevent and treat these conditions at multiple settings, including multiple illustrations, care pathways and tips to easily understand the pathophysiology, diagnostic methods and therapeutic approach to these conditions. This work evaluates the potential for a link between osteoporosis, sarcopenia and obesity. - Presents diagnostic and therapeutic tips that facilitate the design and implementation of new care pathways, impacting the wellbeing of our older population - Provides cross-disciplinary understanding by experts from the bone/osteoporosis field and the muscle/sarcopenia field - Covers muscle and bone biology, mesenchymal stem cells, age-related changes and cross-talk between muscle, fat and bone, falls and fracture risk, glucose metabolism, diagnosis, imaging, and genetics of osteosarcopenia
This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will ...
This book weaves all of these factors together to engage in and promote medical, biomedical and psychosocial interventions, including lifestyle changes, for healthier aging outcomes. The text begins with an introduction to age-related changes that increase in disease and disability commonly associated with old age. Written by experts in healthy aging, the text approaches the principles of disease and disability prevention via specific health issues. Each chapter highlights the challenge of not just increasing life expectancy but also deceasing disease burden and disability in old age. The text then shifts into the whole-person implications for clinicians working with older patients, including the social and cultural considerations that are necessary for improved outcomes as Baby Boomers age and healthcare systems worldwide adjust. Healthy Aging is an important resource for those working with older patients, including geriatricians, family medicine physicians, nurses, gerontologists, students, public health administrators, and all other medical professionals.
The 15th Passive and Low Energy Architecture (PLEA) conference considered the issues of sustainability and environmental friendliness at the city scale. Some 150 papers address the many and varied questions faced by architects and planners in reducing the impact on the environment of cities and their buildings.
This book describes a fully integrated approach to the management of elderly patients who are at risk of or suffer trauma, drawing on up-to-date knowledge from multiple specialties in recognition of the fact that the number and severity of comorbidities in this population requires expertise in many fields. Readers will find comprehensive and detailed coverage of the prevention of complications related to aging, geriatric care concepts, specific treatments in acute care, including fracture stabilization and diagnostic procedures, and the surgical management of different types of fracture and soft tissue trauma. Intensive care management of the geriatric patient is also extensively addressed. Information is provided on diverse aspects of the physiology of ageing, and the coverage is completed by discussion of fracture care service models and specific models of rehabilitation and aftercare designed to prevent further falls and adverse late outcomes. The authors are a group of renowned experts from each of the relevant fields, and the book will be a valuable asset for surgeons, intensivists, geriatricians, gerontologists, and rehabilitation specialists.
This unique book reviews the information available in the literature regarding the new syndrome, frailty, in patients with various renal conditions, such as acute kidney injury, chronic kidney disease, as well as dialysis and transplant patients. The topic is of importance in nephrology, specifically nephrogeriatrics, since frailty is a condition affecting many elderly patients and which is becoming increasingly common in medical practice. As such, there is a considerable need for information to assist professionals treating these patients. The book includes chapters on the frailty syndrome (definition, evaluation and treatment), the main geriatric syndromes (gait disorder, falls, incontinence, and delirium), the main renal syndromes (acute renal injury, chronic kidney disease) as well as dialysis and kidney transplant, and the relationship between geriatrics and renal syndromes. Frailty and Kidney Disease: A Practical Guide to Clinical Management is an essential resource for general practitioners, researchers, internal medicine physicians, geriatricians, and nephrologists.
This book provides in-depth information on Caatinga’s geographical boundaries and ecological systems, including plants, insects, fishes, amphibians, reptiles, birds, and mammals. It also discusses the major threats to the region’s socio-ecological systems and includes chapters on climate change and fast and large-scale land-use changes, as well as slow and small-scale changes, also known as chronic human disturbances. Subsequent chapters address sustainable agriculture, conservation systems, and sustainable development. Lastly, the book proposes 10 major actions that could enable the transformation of Caatinga into a place where people and nature can thrive together. “I consider this b...