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Mechanobiology of Cell-Cell and Cell-Matrix Interactions
  • Language: en
  • Pages: 329

Mechanobiology of Cell-Cell and Cell-Matrix Interactions

Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.

Cell and Matrix Mechanics
  • Language: en
  • Pages: 380

Cell and Matrix Mechanics

  • Type: Book
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  • Published: 2014-10-23
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  • Publisher: CRC Press

Explores a Range of Multiscale Biomechanics/Mechanobiology Concepts Cell and Matrix Mechanics presents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forces in cell–matrix interactions. Providing material in each chapter that builds on the previous chapters, it effectively integrates length scales and contains, for each length scale, key experimental observations and corresponding quantitative theoretical models. Summarizes the Three Hierarchical Levels of Cell Mechanics The book contains 14 chap...

Orthopaedic Biomechanics
  • Language: en
  • Pages: 659

Orthopaedic Biomechanics

  • Type: Book
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  • Published: 2012-12-18
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  • Publisher: CRC Press

Given the strong current attention of orthopaedic, biomechanical, and biomedical engineering research on translational capabilities for the diagnosis, prevention, and treatment of clinical disease states, the need for reviews of the state-of-art and current needs in orthopaedics is very timely. Orthopaedic Biomechanics provides an in-depth review of the current knowledge of orthopaedic biomechanics across all tissues in the musculoskeletal system, at all size scales, and with direct relevance to engineering and clinical applications. Discussing the relationship between mechanical loading, function, and biological performance, it first reviews basic structure-function relationships for most m...

Advanced Materials Modelling for Structures
  • Language: en
  • Pages: 365

Advanced Materials Modelling for Structures

This volume presents the major outcome of the IUTAM symposium on “Advanced Materials Modeling for Structures”. It discusses advances in high temperature materials research, and also to provides a discussion the new horizon of this fundamental field of applied mechanics. The topics cover a large domain of research but place a particular emphasis on multiscale approaches at several length scales applied to non linear and heterogeneous materials. Discussions of new approaches are emphasised from various related disciplines, including metal physics, micromechanics, mathematical and computational mechanics.

The Sounds of Life
  • Language: en
  • Pages: 368

The Sounds of Life

An amazing journey into the hidden realm of nature’s sounds The natural world teems with remarkable conversations, many beyond human hearing range. Scientists are using groundbreaking digital technologies to uncover these astonishing sounds, revealing vibrant communication among our fellow creatures across the Tree of Life. At once meditative and scientific, The Sounds of Life shares fascinating and surprising stories of nonhuman sound, interweaving insights from technological innovation and traditional knowledge. We meet scientists using sound to protect and regenerate endangered species from the Great Barrier Reef to the Arctic and the Amazon. We discover the shocking impacts of noise po...

26th Southern Biomedical Engineering ConferenceSBEC 2010 April 30 - May 2, 2010 College Park, Maryland, USA
  • Language: en
  • Pages: 601

26th Southern Biomedical Engineering ConferenceSBEC 2010 April 30 - May 2, 2010 College Park, Maryland, USA

The 26th Southern Biomedical Engineering Conference was hosted by the Fischell Department of Bioengineering and the A. James Clark School of Engineering from April 30 – May 2 2010.. The conference program consisted of 168 oral presentations and 21 poster presentations with approximately 250 registered participants of which about half were students. The sessions were designed along topical lines with student papers mixed in randomly with more senior investigators. There was a Student Competition resulting in several Best Paper and Honorable Mention awards. There were 32 technical sessions occurring in 6-7 parallel sessions. This Proceedings is a subset of the papers submitted to the conference. It includes 147 papers organized in topical areas. Many thanks go out to the paper reviewers who significantly improved the clarity of the submitted papers.

Plate Structures
  • Language: en
  • Pages: 308

Plate Structures

Plate structures are used in almost every area of engineering, including aerospace and naval architecture, civil engineering, and electronics. These structures have diverse geometries and have to withstand a wide range of loading conditions. This book provides the theoretical foundations of the theories of plates manufactured from various materials, outlines and illustrates the methods used for the analysis of these structures, and emphasizes designs and solution techniques available to an engineer. The book is written for engineers working in industry, graduate students at aerospace, mechanical, civil engineering and naval architecture departments, and investigators interested in the develo...

The Physics of Cancer
  • Language: en
  • Pages: 187

The Physics of Cancer

An introduction to the emerging field of cancer physics, integrating cancer biology with approaches from theoretical and applied physics.

Approximate Analytical Methods for Solving Ordinary Differential Equations
  • Language: en
  • Pages: 584

Approximate Analytical Methods for Solving Ordinary Differential Equations

  • Type: Book
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  • Published: 2014-10-31
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  • Publisher: CRC Press

Approximate Analytical Methods for Solving Ordinary Differential Equations (ODEs) is the first book to present all of the available approximate methods for solving ODEs, eliminating the need to wade through multiple books and articles. It covers both well-established techniques and recently developed procedures, including the classical series solution method, diverse perturbation methods, pioneering asymptotic methods, and the latest homotopy methods. The book is suitable not only for mathematicians and engineers but also for biologists, physicists, and economists. It gives a complete description of the methods without going deep into rigorous mathematical aspects. Detailed examples illustra...

Computational Modeling in Tissue Engineering
  • Language: en
  • Pages: 438

Computational Modeling in Tissue Engineering

One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in: (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying a...