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RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.
Agricultural land is subjected to a variety of societal pressures, as demands for food, animal feed, and biomass production increase, with an added requirement to simultaneously maintain natural areas and mitigate climatic and environmental impacts. The biotic elements of agricultural systems interact with the abiotic environment to generate a number of ecosystem functions that offer services benefiting humans across many scales of time and space. The intensification of agriculture generally reduces biodiversity including that within soil, and impacts negatively upon a number of regulating and supporting ecosystem services. There is a global need toward achieving sustainable agricultural sys...
This fully revised directory of international foundations, trusts, charitable and grantmaking NGOs and other similar non-profit institutions provides a comprehensive picture of foundation activity on a worldwide scale. Now in its 32nd edition, The Europa International Foundation Directory includes: Information on some 2,700 organizations, organized by country or territory, including details of funding priorities and projects, geographical area of activity, principal staff and contact details Details of co-ordinating bodies and centres that assist foundations, grantmaking organizations and other NGOs Bibliography Comprehensive index section This new edition has been revised and expanded to include the most comprehensive and up-to-date information on this growing sector.
Advances in Insect Physiology is committed to publishing volumes containing comprehensive and in-depth reviews on all aspects of insect physiology. First published in 1963, these volumes are an essential reference source for invertebrate physiologists, insect neurobiologists, entomologists, zoologists and insect biochemists. This volume is themed on small RNAs and RNAi in insects. Contains comprehensive and in-depth reviews. Essential reference source for invertebrate physiologists, insect neurobiologists, entomologists, zoologists and insect biochemists. This volume is themed on small RNAs and RNAi in insects.
This book explores the development of nanopesticides and tests of their biological activity against target organisms. It also covers the effects of nanopesticides in the aquatic and terrestrial environments, along with related subjects including fate, behaviour, mechanisms of action and toxicity. Moreover, the book discusses the potential risks of nanopesticides for non-target organisms, as well as regulatory issues and future perspectives.
Now in its 31st edition, the Europa International Foundation Directory 2022 provides an unparalleled guide to the foundations, trusts, charitable and grantmaking NGOs, and other similar not-for-profit organizations of the world. It provides a comprehensive picture of third sector activity on a global scale. Users will find names and contact details for some 2,690 institutions worldwide. This new edition has been revised and expanded to include the most comprehensive and up-to-date information on this growing sector. Indexes allow the reader to find organizations by area of activity (including conservation and the environment, science and technology, education and social welfare) and geographical region of operations (e.g. South America, Central America and the Caribbean, Australasia, Western Europe and North America). Contents include: A comprehensive directory section organized by country or territory; Details of co-ordinating bodies, and of foundations, trusts and non-profit organizations; A full index of organizations, and indexes by main activity and by geographical area of activity.
The publication of the extensive seven-volume work Comprehensive Molecular Insect Science provided a complete reference encompassing important developments and achievements in modern insect science. One of the most swiftly moving areas in entomological and comparative research is endocrinology, and this volume, Insect Endocrinology, is designed for those who desire a comprehensive yet concise work on important aspects of this topic. Because this area has moved quickly since the original publication, articles in this new volume are revised, highlighting developments in the related area since its original publication. Insect Endocrinology covers the mechanism of action of insect hormones durin...
Biopesticides have a great influence in sustainable agriculture, and their use in commercial farming ensures environmental protection, qualitative products, and effective use of resources. The second edition of Biopesticides Handbook is fully updated and includes five new chapters on microbial, biochemical, and RNAi pesticides. It details the benefits of biopesticides along the food chain, offering a full spectrum of the range of organisms and organic products that may be used in the biological control of pests. It discusses the uses and abuses of biopesticides, their positive and negative consequences, as well as more recent advances and the best mode of action to improve environmental safe...
Plants are the basic source of food for both humans and animals. Most of the food is made of fruits and seeds. For these to be formed, pollination must first take place. This process is the transfer of pollen grains from the anther, which is the male structure of the flower, to the sigma on the female structure of the flower. The transfer process requires agents to be carried out. The agents can be either biotic or abiotic. Nature perfected this arrangement between the pollination agents and the plants. As ecosystems and agricultural systems are changing, this balanced arrangement becomes disturbed. This makes it necessary that pollination systems be studied so that necessary measures can be...
Among the highlights of this book is the use of novel insecticides acting on a specific site in an insect group and are compatible with natural enemies and the environment. One of such approaches is based on disrupting the activity of biochemical sites acting on transcription factors such as the Helix-Loop-Helix (bHLH) family, anti juvenile hormone (AJH) agents that target JH biosynthetic enzymes, G-protein coupled receptors (GPCR) and bursicon as a target for insect control. Another one is the biotechnology or the genetic approach such as gene silencing (RNA interference) and Bt-crops. Other sections of the book are devoted to the plant’s natural products, optical manipulation and the use of nanotechnology for improving insect control methods.