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Person
This textbook deals with the grammatical category of person, which covers the first person, the second person, and the third person. Drawing on data from over 700 languages, Anna Siewierska compares the use of person within and across different languages, and examines the factors underlying this variation. She shows how person forms vary in substance, in the nature of the semantic distinctions they convey, in how they are used in sentences and discourse, and in the way they function to convey social distinctions. By looking at different types of person forms in the grammatical and social contexts in which they are used, this book documents an underlying unity between them, arguing against the treatment of person markers based on arbitrary sets of morphological and syntactic properties. Clearly organized and accessibly written, it will be welcomed by students and scholars of linguistics, particularly those interested in grammatical categories and their use.
Boyd's Blue Book
None
Advances in Neurochemistry
In the Preface to Volume 1, we stated: This series recognizes that investigators who have entered neurochemistry from the biochemical tradition have a rather specialized view of the brain. Too often, interdisci plinary offerings are initially attractive but turn out to recite basic biochemical considera tions. We have come to believe that there are now sufficiently large numbers of neurochemists to support a specialized venture such as the present one. We have begun with consideration of traditional areas of neurochemistry which show considerable scientific activity. We hope they will serve the neurochemist both for general reading and for specialized information. The reader will also have t...
Nutritional Management of Genetic Disorders
Abstract: The relationships between genetic diseases anddiet are analyzed for the physician or nutritionistinterested in understanding the utility of basic nutritional management in the treatment of these diseases. The material covered includes: vitamin D-resistant rickets; dietaryrestriction and use of cofactors and keto acids in inbornerrors of amino acid metabolism; intolerance of lactose andother carbohydrates; diabetes; genetic obesity;hyperlipidemias; and lipids in cystic fibrosis. (wz).
Iron Metabolism
International Symposia sponsored by ClBA Basle have been held once a year since 1959 in various European countries. In con trast to the many scientific meetings organised by the ClBA FOUN DATION either at its headquarters in London or occasionally abroad, the subjects dealt with at these International Symposia have con cerned problems more directly related to ClBA'S own research work in the pharmaceutical field. The various topics covered up to the present reflect the far-reaching interests and the wide spread activities that a pharmaceutical enterprise develops in quite diverse fields of chemical, biological, and medical research, and to which the ba.sic approach is an increasingly importan...
Progress in Medicinal Chemistry
Progress in Medicinal Chemistry
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays
Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily ...
The Alkaloids
The Alkaloids: Chemistry and Physiology, Volume VIII: The Indole Alkaloids focuses on the advances in the chemistry of indole alkaloids. This book discusses the tryptamine and its derivatives, postulated biosyntheses of the physostigmine ring system, and source of the alkaloids. The simple lysergic acid amides, mass spectra of mitraphylline and rhynchophylline, and alkaloids of gelsemium species are also elaborated. This text likewise covers the determination of the structure of the alkaloids, stereochemistry of cinchonamine, dimeric alkaloids of calabash curare, and chemistry of the reserpine group. Other topics include the biology of ergot and short history of its active principles up to the discovery of ergotamine. This volume is recommended for chemists and researchers interested in indole alkaloids.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
