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This book grew out of the conviction that the preparation and management of large-scale technological projects can be substantially improved. We have witnessed the often unhappy course of societal and political decision making concerning projects such as hazardous chemical installations, novel types of electric power plant or storage sites for solid wastes. This has led us to believe that probabilistic risk analysis, technical reliability analysis and environm,ental impact analysis are necessary but insufficient for making acceptable, and justifiable, social decisions about such projects. There is more to socio-technical decision making than applying acceptance rules based on neglige ably lo...
Development and status of landscape ecology - subject of this book During the last decades, landscape ecology has developed tremendously. It concerns both the theoretical basis and practical application. The roots of landscape ecology are geography and biology. The term "landscape ecology" was first coined by the German scientist Carl Troll in 1939. ünce, the devel opment center of landscape ecology was in Central Europe. Recently, also other parts of the world became powernd centers of landscape ecology, es pecially Northern America. American approaches partly differ essentially from the European, because they are focused esp. on biogeography and population dynamics. In Europe, however, th...
The term “Artificial Intelligence” has been used since 1956 and has become a very popular research field. Generally, it is the study of the computations that enable a system to perceive, reason and act. In the early days, it was expected to achieve the same intelligent behavior as a human, but found impossible at last. Its goal was thus revised to design and use of intelligent methods to make systems more ef- cient at solving problems. The term “Applied Intelligence” was thus created to represent its practicality. It emphasizes applications of applied intelligent systems to solve real-life problems in all areas including engineering, science, industry, automation, robotics, business,...
In this volume, the medicinal chemistry of the rapidly expanding family of retinoids, of promising semi-synthetic erythromycins and of the multifaceted amidines is reviewed. Another chapter continues the coverage of inorganic elements which have a medical role; recent studies on the various biological roles of manganese are also examined. Inhibition of enkephalin-degrading enzymes is reviewed, as are studies of the digitalis recognition site which are expected to lead to the development of more highly selective inotropic drugs. This work should be of value to medicinal chemists, pharmacists and pharmacologists. It should also be appreciated by all newcomers, as well as those who wish to be kept up to date with recent work on these topics.
The Europaische Akademie zur Erforschung von Folgen wissenschaftlich-techni scher Entwicklungen Bad Neuenahr-Ahrweiler GmbH (european academy) is con cerned with the scientific study of the consequences of scientific and technological advance for the individual and social life and for the natural environment. The main focus is to examine foreseeable mid-and long-term processes that are especially influenced by natural-and engineering sciences and the medical disciplines. The academy fulfills this task by organizing interdisciplinary expert discussions. Another important issue of the work of the Europaische Akademie concerns the methodology of Technology Assessment as a general issue. This is...
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atmosphere and vegetation. In what ways can key ural and cultural functions of water, primarily elements of the water balance and the hydrological through direct interference by agriculture and cycle be altered by climate change? To answer this through pollutant loads emanating from point and question, the Council presents an analysis in which non-point sources in settlements, the small business characteristics of the hydrological cycle under pre sector, agriculture and industry. Too little is known sent climatic conditions are compared to those in a about the behavior of substances that enter water simulated climate with CO doubling (equivalent to through human activities, about their decom...
Southern society.
This book aims to provide a state-of-the-art summary of what is currently known about brain glycogen metabolism, detailing the recent advances in our understanding of why glycogen is so critical for normal brain function. The role of glycogen in cellular neurophysiology remains largely unclear and its specific contribution to the energy demand of brain cells is still elusive.Glycogen is the sole cerebral glucose reserve and is emerging as a fundamental component of brain energy metabolism. Pharmacological or genetic manipulation of glycogen metabolism in the brain impairs memory formation and increases susceptibility to epileptic seizures and cortical spreading depression. Glycogen is also directly implicated in abnormal neuronal excitability and mental retardation that characterize brain disorders like Lafora disease and Pompe disease.