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This work has true international scope, being a unique European/American joint venture that focuses on the state of the art in both diagnostic and therapeutic radionuclide methodology. Pertinent clinical applications are emphasized rather than attempting to cover everything included in the several large comprehensive texts available in our field. This "practical" approach should make it an essential guide to nuclear medicine physicians, technologists, students and interested clinicians alike.
Clinical studies during the past 10 years have shown that PET is more sensitive than CT and MRI for the detection of many tumors. In many cases, however, for example in head and neck tumors, combination with radiological procedures is necessary. It may be speculated that PET should be the first study in a malignant tumor when metastatic spread is suspected. MRI and CT may then be restricted to those body areas which evince sites of increased glucose metabolism. Thus, a combination of metabolic and morphologic procedures will enhance tumor detection and change the therapeutic strategy. In this light, an atlas including PET, CT, MRI, and histology data seems desirable to combine metabolic and morphologic imaging. This book presents an overview of the available data which should be of great interest not only for specialists in radiology and nuclear medicine, but also for oncologists.
- Includes all current diagnostic techniques including FDG-PET and MRI - Second Edition is completely revised to include the latest diagnostic and theraputic concepts - Special section is devoted to medullary thyroid cancer
This book provides a comprehensive survey of the pharmacokinetic models used for the quantitative interpretation of contrast-enhanced imaging. It discusses all the available imaging technologies and the problems related to the calibration of the imaging system and accuracy of the estimated physiological parameters. Enhancing imaging modalities using contrast agents has opened up new opportunities for going beyond morphological information and enabling minimally invasive assessment of tissue and organ functionality down to the molecular level. In combination with mathematical modeling of the contrast agent kinetics, contrast- enhanced imaging has the potential to provide clinically valuable a...
There can never be enough material in the public domain about cancers, and particularly breast cancer. This book adds much to the literature. It provides general information on breast cancer management and considers all new methods of diagnosis and therapy. It focuses on nuclear medicine modalities by comparing their results with other diagnostic and therapeutic approaches. The coverage provides readers with up-to-date knowledge on breast cancer as well as information on the advances in the field of diagnosis. It also details data on the development of some new modalities and provides a general overview of the available tools for breast cancer treatment.
During the last decade many significant advances have been made in the in vivo diagnosis of disease. An area of partic ular success has been the application of nuclear medical procedures to the detection of cardiac disease. Not only is it possible to detect infarction or ischemia by scintigraphic techniques but by the use of labelled metabol ites and analogues of potassium the viability of myocardial tissue can be evaluated. The efficiency of the heart pump can be calculated and wall motility observed in one simple proce dure. The use of ultra short life radionuclides has made the evaluation of rapid changes in myocardial function feasible. Altogether a broad and impressive diagnostic packag...
The introduction of nuclear medicine into oncology dates back to the early 1 940s, when Lawrence reported on the tumor retention of 32P-phosphate, von Hevesy and von Euler soon afterwards published their fundamental work on the metabolism of phosphorus in sarcoma cells, and when almost at the same time Keston and his coworkers de scribed their observation of the accumulation of radioactive iodine in metastases of a thyroid carcinoma. Since that time innumerable publi cations have appeared in oncologic literature which deal with the application of nuclear medical methods in experimental cancer re search and also in the diagnosis and treatment of malignant tumors. The significance of some orig...
PRACTICAL FDG IMAGING provides the reader with a reference source of cases with FDG images obtained both on dedicated PET tomographs and hybrid scintillation cameras. The cases are presented in thorough depth so that they are of value to both specialists and residents in training who need to learn the indications and interpretations of FDG images and the advantages and limitations of hybrid scintillation cameras compared to dedicated PET tomographs. This book is ideal for nuclear and radiology medicine residents, as well as those practitioners who need to become familiar with this technology. The first part of the book concentrates on the technical aspects of FDG imaging. Part two is devoted to the clinical applications in the fields of neurology, cardiology and oncology.
Tailoring treatment for individual breast cancers is no longer a dream and is now the main goal for current research. This book gives an overview of the most recent techniques, agents and approaches for breast cancer and the individualization of treatment. Particular attention is given to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation. Contributions from experts focus on the biomedical research behind the transfer of molecular biology knowledge into the clinical management of patients. This has led to increased survival as well as improved quality of life. The book gives an overview of the latest achievements in breast cancer and their use in clinical practice.