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Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic co...
Meta-Analysis shows concisely, yet comprehensively, how to apply statistical methods to achieve a literature review of a common research domain. It demonstrates the use of combined tests and measures of effect size to synthesize quantitatively the results of independent studies for both group differences and correlations. Strengths and weaknesses of alternative approaches, as well as of meta-analysis in general, are presented.
W.A. de Jong President of TNO Until some decades ago man supposed that the resilience of the environment was unlimited. He thought he could draw heavily on nature with impunity and that he could infinitely dump his waste into the environment. We have come to know better now: virtually everyone is well aware that one cannot just go on burdening the environment of man, animal and plant to such an extent. TNO, the Netherlands Organization for Applied Scientific Research, is among those research institutions that are working on economically feasible solutions for pollution problems resulting from human activities. Soil contamination and remediation feature as important topics in TNO's environmen...
The developments in the area of ordered nanoporous solids have moved beyond the traditional catalytic and separation uses and given rise to a wide variety of new applications in different branches of chemistry, physics, material science, etc. The activity in this area is due to the outstanding properties of nanoporous materials that have attracted the attention of researchers from different communities. However, recent achievements in a specific field often remain out of the focus of collaborating communities. This work summarizes the latest developments and prospects in the area of ordered porous solids, including synthetic layered materials (clays), microporous zeolite-type materials, orde...