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This volume presents a collection of papers dealing with various aspects of clustering in biological networks and other related problems in computational biology. It consists of two parts, with the first part containing surveys of selected topics and the second part presenting original research contributions. This book will be a valuable source of material to faculty, students, and researchers in mathematical programming, data analysis and data mining, as well as people working in bioinformatics, computer science, engineering, and applied mathematics. In addition, the book can be used as a supplement to any course in data mining or computational/systems biology.
Describes general aspects of metals in clinical chemistry focusing not only on the physiology of metal ions and their analytical determination in biological materials, but also on their geochemical distribution, technical uses and environmental effects.
Source control is the key to the management of surgical infections. Surgical decision making is based on the marriage of evidence from clinical studies, inferences from biology, and the elusive component of surgical experience; this book combines these three elements. We have recruited an international group of authors who are acknowledged leaders in the field of surgical infectious diseases. We have challenged them to integrate evidence with experience and an understanding of biology so as to create overviews that will help the clinician who must make the difficult decisions. And we have kept them honest by asking a second group of equally eminent commentators to provide supporting or alternative views - in essence, to recreate the kind of dialogue that takes place between clinicians discussing a difficult problem. This is THE manual for the authoritative management of surgical infections!
After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Ed...
This work provides specific infection parameters for bacterial infections, and indicators for the inflammatory activity of sepsis and multi-organ failure.
Aluminium is the most abundant metal ion in the biosphere and we are continuously exposed to it in our everyday life through food, beverages, pharmaceutical products, etc. This book is a current and comprehensive review of the biochemistry, metabolism and toxicity of aluminium undertaken by an international group of authors, many of whom are outstanding authorities in their respective fields. In contrast with previous books on this topic, much of the subject matter is unique, in that it is primarily directed at aluminium nutrition and toxicity in infants and children. This book covers many aspects of aluminium toxicity in infants including for instance the embryo-fetal as well as the neurodevelopmental effects of this element, contamination of pharmaceutical products, and individual sensitivity through vaccines using aluminium as an adjuvant.This book will be especially useful to paediatricians, paediatric nephrologists & neurologists, nutritionists, toxicologists, biochemical toxicologists and postgraduate students.
The molecular pathogenesis of microbial agents responsible for respiratory tract infections (RTIs) has been the focus of much research in recent years. The emphasis has been on developing new treatments such as novel antimicrobials and more effective vaccines. Significant attention has also been paid to improving molecular diagnostic methods to identify RTI-causing microbes, as well as understanding the host response to them. The Microbe-Host Interface in Respiratory Tract Infections presents an overview of the current knowledge in this area. It provides us with the first coherent picture of emerging strategies for controlling the microbes responsible for RTIs. This comprehensive volume is d...
The traditional approach to kidney disorders is changing. In the field of diagnostics much innovative research is ongoing: from the “old” embryology, revisited and re-interpreted with new eyes in the light of immunohistochemistry, up to metabolomics the latest “daughter” of genomics, the most promising and remarkable of the “omics” disciplines. Between these two extremes we find a universe of novelties, ranging from the most recent urinary biomarkers to the questions of nutrition and growth, as well as those of ethics, which the new populations of extremely low birth weight (ELBW) neonates present to neonatologists and nephrologists. The studies on perinatal programming expands t...