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Computer-Assisted Musculoskeletal Surgery
Computer-Assisted Surgery (CAS) is a new tool for performing complex procedures in a predictable and safe way. This book is designed to serve as a comprehensive review of Computer-Assisted Surgery, covering the current status of both research and applications. CAS includes Virtual Preoperative Planning (VPP) and Intraoperative Virtual Navigation (IVN), which are a set of technologies used to measure oncological margins in 3-Dimensions (3D), to locate small intraosseous tumors and apply controlled resections preserving anatomical structures. During VPP, patient acquired multimodal images are processed and an interactive virtual scenario is created. This can then be used as a platform to measure oncological distances and preplan osteotomies in safe areas. IVN is a procedure which allows the execution of the VPP with a mean error of less than 3mm. For the student, medical doctors, research and development scientists or new researchers, the protocols are central to the performance of Computer-Assisted technologies.
Cancer Cell Lines Part 1
Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines ...
Experimental Investigations into Sarcomas
Manfred Georg Krukemeyer first describes magnetic drug targeting, by which is meant the focused application of drugs, e.g. the introduction of a cytostatic, and which is aimed at optimising its locally therapeutic effect. The author thus achieves a high concentration of cytostatic at the site of the tumour. The particles have to be large enough to be attracted by a magnetic field and so find their way into the tumour, where they release their active ingredient. The aim of the hypothesis formed by one of the author’s study groups was to show in a scientific experiment that in this case cytostatics coupled with iron particles [Fe3O4] can be introduced into a tumour. The focused introduction of drugs – magnetic drug targeting – results in faster arrival of the active ingredient at the target site together with a reduced quantity of active substances. For this reason magnetic drug targeting is also interesting from an economic point of view.
Cancer Research Supported Under BIOMED 1
The pace of discovery, within the EU, of scientific aspects of cancer research and of developments in the clinical field is so rapid that it is sometimes difficult to keep abreast. This brief overview attempts to highlight some of the advances in the field, as part of BIOMED programme funded research and specific results due to the co-operative spirit established by the scientific community. It is particularly worth noting the financial investment of 35 million ECU in the current programme, has d as a catalyst in attracting a large number of Member States funded research in pooling their collective knowledge base.
Seeing Babies in a New Light
This book is about the life and work of Hanus Papousek (1922-2000) who was a major contributor to modern developmental psychology. This book is intended for students, teachers, and professionals in the fields of developmental psychology, early childhood
Chaos and Fractals
For almost ten years chaos and fractals have been enveloping many areas of mathematics and the natural sciences in their power, creativity and expanse. Reaching far beyond the traditional bounds of mathematics and science to the realms of popular culture, they have captured the attention and enthusiasm of a worldwide audience. The fourteen chapters of the book cover the central ideas and concepts, as well as many related topics including, the Mandelbrot Set, Julia Sets, Cellular Automata, L-Systems, Percolation and Strange Attractors, and each closes with the computer code for a central experiment. In the two appendices, Yuval Fisher discusses the details and ideas of fractal image compression, while Carl J.G. Evertsz and Benoit Mandelbrot introduce the foundations and implications of multifractals.
Music and the Mind Machine
Research in music is a multidisciplinary matter. Experts from very different fields in science report the most recent data from their own research and thereby show today's knowledge concerning music and neuropsychological sciences. This includes the developing and adult brain, neurological and psychiatric diseases as well as the battery of the most recent development in brain imaging techniques. This book offers an excellent introduction to new scientific efforts in understanding both neuronal and psychic mechanisms when listening to or performing music.
Transplantation in Hematology and Oncology II
Transferring hematopoietic stem cells and immune cells has continued to be a promising therapeutic alternative and a fascinating area of cell biology as well as a field of persistent procedural problems. This explains why substantial parts of basic research on cell growth and differentiation, immune tolerance and antitumor effects, gene transfer, minimal residual disease and supportive care have settled around clinical transplantation in hematology and oncology. This second volume updates the current role of allogeneic and autologous transplantation in leukemias, lymphomas and solid cancers, including controversial strategies and novel experimental approaches. Outstanding representatives of leading groups guarantee first-hand information and indicate how we can work and cooperate more effectively to the benefit of our patients.
Fractal Geometry and Computer Graphics
Fractal geometry has become popular in the last 15 years, its applications can be found in technology, science, or even arts. Fractal methods and formalism are seen today as a general, abstract, but nevertheless practical instrument for the description of nature in a wide sense. But it was Computer Graphics which made possible the increasing popularity of fractals several years ago, and long after their mathematical formulation. The two disciplines are tightly linked. The book contains the scientificcontributions presented in an international workshop in the "Computer Graphics Center" in Darmstadt, Germany. The target of the workshop was to present the wide spectrum of interrelationships and...
Fractals in Science
A deeply detailed discussion of fractals in biology, heterogeneous chemistry, polymers, and the earth sciences. Beginning with a general introduction to fractal geometry it continues with eight chapters on self-organized criticality, rough surfaces and interfaces, random walks, chemical reactions, and fractals in chemisty, biology, and medicine. A special chapter entitled "Computer Exploration of Fractals, Chaos, and Cooperativity" presents computer demonstrations of fractal models: 14 programs are included on a 3 1/2" MS-DOS diskette which run on any PC with at least 1 MB RAM and a EGA or VGA graphics card, 16 colors.
