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Listen to the Music
  • Language: en
  • Pages: 310

Listen to the Music

Dr. Hilary Koprowski is the pioneer of live polio vaccine, the first researcher to advance the diagnostic and therapeutic use of monoclonal antibodies, and the developer of the "gold standard" rabies vaccine. A world-reknowned maverick in biomedical research, Koprowski's research methods were often considered controversial and even radical. Nonetheless, he acquired key positions in many research organizations, such as the Rockefeller Foundation, Lederle Labs, and Wistar Institute, initiating landmark studies from cancer research to multiple sclerosis. One of his crowning achievements, the successful crusade for monoclonal antibodies, resulted in his founding of Centocor, a forerunner in the corporate world of biomedicine. This account of Koprowski's life history is a mixture of personal interviews, anecdotes, and legends of the art and science behind the man.

Human Immunogenetics
  • Language: en
  • Pages: 849

Human Immunogenetics

  • Type: Book
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  • Published: 2020-10-28
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  • Publisher: CRC Press

Delineating fundamental concepts of contemporary immunogenetics, this reference/text examines specific immunogenetic systems in terms of molecular biochemistry and immunophysiology. Covers material in diverse fields, including infectious diseases, cell biology, virology, molecular genetics. Comprise

Research Awards Index
  • Language: en
  • Pages: 944

Research Awards Index

  • Type: Book
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  • Published: Unknown
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  • Publisher: Unknown

None

The Lock and Key of Medicine
  • Language: en
  • Pages: 345

The Lock and Key of Medicine

This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies, or Mabs. Though unfamiliar to most nonscientists, these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. They have radically changed understandings of the pathways of disease, enabling faster, cheaper, and more accurate clinical diagnostic testing. And they lie at the heart of the development of genetically engineered drugs such as interferon and blockbuster personalized therapies such as Herceptin. Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs who ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, controversies over Mabs remain, which the author explores through the current debates on their cost-effectiveness.

Infectious Diseases of Wild Mammals
  • Language: en
  • Pages: 576

Infectious Diseases of Wild Mammals

Infectious Diseases of Wild Mammals, Third Edition presents the latest information on the diagnosis and treatment of infectious disease in both free-ranging and captive wild mammals. Editors Elizabeth Williams and Ian Barker have recruited 71 contributors, all noted experts in their fields, to update this new edition. This reference provides valuable information on each disease, including Etiology History Distribution Epidemiology Clinical signs Pathology Immunity Diagnosis Treatment Control This latest edition is a leading reference book for Wildlife biologists, managers, and rehabilitators Biology students Conservationists Public health workers

Rabies
  • Language: en
  • Pages: 730

Rabies

Rabies: Basis of the Disease and Its Management, Fourth Edition is an authoritative reference on the current status of rabies, including the virological, clinical, and public health aspects and management recommendations. Rabies remains one of the most important global public health problems worldwide. Although many important developments have been made over the past century to combat this disease, rabies has become a re-emergent infection in the resource-constrained countries. The Fourth Edition updates this classic reference with comprehensive coverage of the molecular virology, pathogenesis, immunology, vaccines, public health aspects, and epidemiology of rabies and is completely revised, with new chapters that will cover historical developments in rabies intervention strategies, the evolution of rabies virus, modeling rabies control, and on the strategy for rabies elimination. Rabies, Fourth Edition, provides physicians, veterinarians, public health advisors, epidemiologists, and research scientists with a single source for authoritative and up-to-date information on the diagnosis, treatment, control, and prevention of this fatal infectious virus.

Research Grants Index
  • Language: en
  • Pages: 854

Research Grants Index

  • Type: Book
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  • Published: 1969
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  • Publisher: Unknown

None

The Biology of DNA Tumor Viruses
  • Language: en
  • Pages: 265

The Biology of DNA Tumor Viruses

Milestones in Current Research is a series of reprint collections dis tinguished from other such publications by new concepts in preparation, presentation, and intent. The aim of each volume is to gather for a given field the seminal contributions that have defined and shaped the trends within the most active areas of current research. The selections for each volume and the structure of the book have been determined with the help of a novel tech nique of bibliographic analysis and have then been presented to an acknowl edged scientific authority for minor adjustments and the writing of an In troduction. These introductions will lend historic perspective to the material selected for each volu...

Advances in Immunology
  • Language: en
  • Pages: 389

Advances in Immunology

Advances in Immunology

The Natural History of Rabies, Volume 1
  • Language: en
  • Pages: 477

The Natural History of Rabies, Volume 1

  • Type: Book
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  • Published: 2012-12-02
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  • Publisher: Elsevier

The Natural History of Rabies, Volume I explores the fundamental aspects of the rabies virus, including its growth, latency, morphology, chemistry, physical characteristics, and relationships with other viruses. It looks at the virus' in vivo pathogenesis and pathology, from entrance to transmission in the central nervous system (CNS) and subsequent exit. It also reviews current diagnostic methods including those used for antibody titration and for determination of virus presence. Organized into three sections encompassing 21 chapters, this volume begins with an overview of the history of rabies as well as its morphology and morphogenesis. It then discusses the virus' antigenic composition a...